Cytotoxic Cembrenolides and Steroids from the Formosan Soft Coral Sarcophyton Crassocaule

Overview

Journal J Nat Prod

Date 2001 Jan 5

PMID 11141104

Citations 23

Authors

C Y Duh

S K Wang

S G Chung

G C Chou

C F Dai

Affiliations

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Abstract

Three new cytotoxic cembrenolide diterpenes, sarcocrassolide (1), crassolide (2), and 13-acetoxysarcocrassolide (3); a known cytotoxic cembrenolide, denticulatolide (4); and two cytotoxic steroids, (24S)-24-methylcholestane-3beta,5alpha,6beta-triol (5) and 24zeta-methylcholestane-3beta,5alpha,6beta,25-te traol-25-monoacetate (6), have been isolated from the Formosan soft coral Sarcophyton crassocaule. The structures of compounds 1-6 were determined by 1D and 2D spectral analysis.

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