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Nucleotide Sequence of Salmon Testes and Salmon Liver Cytoplasmic Initiator TRNA

Overview
Journal Cell
Publisher Cell Press
Specialty Cell Biology
Date 1975 Nov 1
PMID 1053250
Citations 30
Authors
A M Gillum
N Urquhart
M Smith
U L RajBhandary
Affiliations
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Abstract

Initiator tRNAs from the cytoplasm of salmon testes and salmon liver have been purified. The nucleotide sequence of these initiator tRNAs has been determined and found identical to that of initiator tRNA from mammalian cytoplasm. The only difference is the extent of modification of the nuceloside located between the dihydrouridine and the anticodon stems. In the salmon tRNAs, this modified nucleoside is predominantly N2N2-dimethyl guanosine, whereas in the mammalian initiator tRNA it is N2-methyl guanosine.

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