Structure of the Respiratory NADH:ubiquinone Oxidoreductase (complex I)

Overview

Journal Curr Opin Struct Biol

Date 1999 Aug 17

PMID 10449365

Citations 15

Authors

N Grigorieff

Affiliations

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Abstract

Three-dimensional structures of NADH:ubiquinone oxidoreductase (or complex I) from the respiratory chain of mitochondria and bacteria have been recently studied by electron microscopy. The low-resolution structures all reveal a characteristic L shape for complex I; however, some of the differences among these structures may have important implications for the location of the functional elements of complex I, for example, the ubiquinone-binding site.

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