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N Grigorieff

Explore the profile of N Grigorieff including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 676
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Recent Articles
1.
Grigorieff N
Methods Enzymol . 2016 Aug; 579:191-226. PMID: 27572728
Frealign is a software tool designed to process electron microscope images of single molecules and complexes to obtain reconstructions at the highest possible resolution. It provides a number of refinement...
2.
Wolf M, Eberhart A, Glossmann H, Striessnig J, Grigorieff N
J Mol Biol . 2003 Aug; 332(1):171-82. PMID: 12946355
The three-dimensional structure of the skeletal muscle voltage-gated L-type calcium channel (Ca(v)1.1; dihydropyridine receptor, DHPR) was determined using electron cryo-microscopy and single-particle averaging. The structure shows a single channel complex...
3.
Sokolova O, Grigorieff N
Structure . 2001 Apr; 9(3):215-20. PMID: 11286888
Background: The voltage-gated potassium channel Shaker from Drosophila consists of a tetramer of identical subunits, each containing six transmembrane segments. The atomic structure of a bacterial homolog, the potassium channel...
4.
Mindell J, Maduke M, Miller C, Grigorieff N
Nature . 2001 Feb; 409(6817):219-23. PMID: 11196649
Virtually all cells in all eukaryotic organisms express ion channels of the ClC type, the only known molecular family of chloride-ion-selective channels. The diversity of ClC channels highlights the multitude...
5.
Nogales E, Grigorieff N
J Cell Biol . 2001 Jan; 152(1):F1-10. PMID: 11149934
No abstract available.
6.
Grigorieff N
Acta Crystallogr D Biol Crystallogr . 2000 Sep; 56(Pt 10):1270-7. PMID: 10998623
Analytical expressions are derived and computer simulations are presented to assess the accuracy of procedures commonly used to estimate the resolution of three-dimensional (3D) structures derived from images of single...
7.
Grigorieff N
Curr Opin Struct Biol . 1999 Aug; 9(4):476-83. PMID: 10449365
Three-dimensional structures of NADH:ubiquinone oxidoreductase (or complex I) from the respiratory chain of mitochondria and bacteria have been recently studied by electron microscopy. The low-resolution structures all reveal a characteristic...
8.
Smith C, Grigorieff N, Pearse B
EMBO J . 1998 Sep; 17(17):4943-53. PMID: 9724631
We present a map at 21 A resolution of clathrin assembled into cages with the endocytic adaptor complex, AP-2. The map was obtained by cryo-electron microscopy and single-particle reconstruction. It...
9.
Grigorieff N
J Mol Biol . 1998 May; 277(5):1033-46. PMID: 9571020
NADH:ubiquinone oxidoreductase (complex I) is the first and largest complex in the electron transport chain of mitochondria. The bovine complex purified from cardiac muscle consists of at least 42 different...
10.
Grigorieff N, Ceska T, Downing K, Baldwin J, Henderson R
J Mol Biol . 1996 Jun; 259(3):393-421. PMID: 8676377
Using electron diffraction data corrected for diffuse scattering together with additional phase information from 30 new images of tilted specimens, an improved experimental density map has been calculated for bacteriorhodopsin....