Synthesis
Overview
Synthesis is a multidisciplinary journal that publishes cutting-edge research in the fields of chemistry, biology, and materials science. It provides a platform for scientists to share their innovative synthetic methodologies, strategies, and techniques, fostering collaboration and advancing knowledge in the synthesis of organic and inorganic compounds, natural products, pharmaceuticals, and functional materials. With a focus on originality and quality, Synthesis serves as a valuable resource for researchers, academics, and industry professionals seeking to stay at the forefront of synthetic s
Details
Details
Metrics
Metrics
h-index / Ranks: 1321
155
SJR / Ranks: 7756
582
CiteScore / Ranks: 4922
5.10
JIF / Ranks: 4138
2.6
Recent Articles
11.
Zebrowski P, Roser K, Chrenko D, Pospisil J, Waser M
Synthesis (Stuttg)
. 2024 Jun;
55(11):1706-1713.
PMID: 38855403
The enantioselective addition of isoxazolidin-5-ones to the β-carbon of allenoates has been carried out by using a novel spirobiindane-based quaternary ammonium salt catalyst. This protocol, which proceeds under classical liquid-solid...
12.
Dehnert B, Dworkin J, Kwon O
Synthesis (Stuttg)
. 2024 Jun;
56(1):71-86.
PMID: 38832211
This review highlights the history and recent advances in dealkenylative functionalization. Through this deconstructive strategy, radical functionalizations occur under mild, robust conditions. The reactions described proceed with high efficiency, good...
13.
Forsythe N, Mize E, Kashiwagi G, Demchenko A
Synthesis (Stuttg)
. 2024 Apr;
56(7):1147-1156.
PMID: 38655286
Superarmed glycosyl donors have higher reactivity compared to their perbenzylated armed counterparts. Generally, the 2-- benzoyl-3,4,6-tri--benzyl protecting group pattern gives rise to increased reactivity due to an O-2/O-5 cooperative effect....
14.
Dutta S, Bhatt K, Cuffel F, Seidel D
Synthesis (Stuttg)
. 2024 Feb;
55(15):2343-2352.
PMID: 38314182
Secondary alicyclic amines are converted to their corresponding ring-fused imidazoles in a simple procedure consisting of oxidative imine formation followed by a van Leusen reaction. Amines with an existing α-substituent...
15.
Liu Y, Woerpel K
Synthesis (Stuttg)
. 2024 Jan;
55(15):2261-2272.
PMID: 38249784
Carbometallation of alkenes and alkynes are powerful carbon-carbon bond-forming reactions. The use of compounds containing bonds between carbon and group 13 elements, particularly boron and aluminum, are particularly attractive because...
16.
Gillard R, Zhang J, Steel R, Wang J, Strull J, Cai B, et al.
Synthesis (Stuttg)
. 2023 Dec;
56(1):118-133.
PMID: 38144170
Retrosynthetic deconstruction of a core aromatic ring is an especially simplifying retrosynthetic step, reducing the complexity of the precursor synthetic target. Moreover, when implemented to provide a penultimate intermediate, it...
17.
Intelli A, Pal M, Selvaraju M, Altman R
Synthesis (Stuttg)
. 2023 Nov;
55(21):3568-3574.
PMID: 37915377
A Pd-catalyzed decarboxylative dearomatization reaction of a heterocyclic substrate enables access to an uncommon reaction intermediate that rearomatizes in the presence of amine bases in a net C-H functionalization sequence....
18.
Ortiz E, Saludares C, Wu J, Cho Y, Santana C, Krische M
Synthesis (Stuttg)
. 2023 Oct;
55(10):1487-1496.
PMID: 37841289
The evolution of methods for carbonyl allylation and crotylation of alcohol proelectrophiles culminating in the design of iodide-bound ruthenium-JOSIPHOS catalysts is prefaced by a brief historical perspective on asymmetric carbonyl...
19.
Barker T, Bogatkevich A, Crowder D, Gierszal S, Hayes J, Hollerbach M, et al.
Synthesis (Stuttg)
. 2023 Oct;
55(17):2639-2647.
PMID: 37790600
This short review summarizes our laboratory's development of benzylboronic esters as nucleophiles. Activation of the benzylboronic ester is achieved by irreversible coordination of an alkyllithium Lewis base to form a...
20.
Scheerer J, Leeth E, Sprow J
Synthesis (Stuttg)
. 2023 Sep;
55(15):2319-2324.
PMID: 37691879
A new method to prepare 1,4-oxazinone intermediates was developed based on aza-conjugate addition of β-amino alcohols to electron-deficient alkyne precursors. A tandem intramolecular cycloaddition/cycloreversion reaction sequence was evaluated, leading to...