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Nuclear Receptor

Nuclear Receptor is a scientific journal, published since 2003 in English. The journal's country of origin is United Kingdom.
Details
Abbr. Nucl Recept
Start 2003
End 2007
e-ISSN 1478-1336
Country United Kingdom
Language English
Recent Articles
1.
The integration of lipid-sensing and anti-inflammatory effects: how the PPARs play a role in metabolic balance
Nunn A, Bell J, Barter P
Nucl Recept . 2007 May; 5(1):1. PMID: 17531095
The peroxisomal proliferating-activated receptors (PPARs) are lipid-sensing transcription factors that have a role in embryonic development, but are primarily known for modulating energy metabolism, lipid storage, and transport, as well...
2.
Association of common variation in the PPARA gene with incident myocardial infarction in individuals with type 2 diabetes: a Go-DARTS study
Doney A, Fischer B, Lee S, Morris A, Leese G, Palmer C
Nucl Recept . 2005 Nov; 3:4. PMID: 16309557
Background: Common variants of the PPARA gene have been found to associate with ischaemic heart disease in non diabetic men. The L162V variant was found to be protective while the...
3.
Gene expression profiling of potential peroxisome proliferator-activated receptor (PPAR) target genes in human hepatoblastoma cell lines inducibly expressing different PPAR isoforms
Tachibana K, Kobayashi Y, Tanaka T, Tagami M, Sugiyama A, Katayama T, et al.
Nucl Recept . 2005 Oct; 3:3. PMID: 16197558
Background: Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors and commonly play an important role in the regulation of lipid homeostasis. To identify human PPARs-responsive genes, we established tetracycline-regulated human...
4.
Evolutionary selection across the nuclear hormone receptor superfamily with a focus on the NR1I subfamily (vitamin D, pregnane X, and constitutive androstane receptors)
Krasowski M, Yasuda K, Hagey L, Schuetz E
Nucl Recept . 2005 Oct; 3:2. PMID: 16197547
Background: The nuclear hormone receptor (NR) superfamily complement in humans is composed of 48 genes with diverse roles in metabolic homeostasis, development, and detoxification. In general, NRs are strongly conserved...
5.
Thyroid hormone receptor binding to DNA and T3-dependent transcriptional activation are inhibited by uremic toxins
Santos G, Pantoja C, Costa E Silva A, Rodrigues M, Ribeiro R, Simeoni L, et al.
Nucl Recept . 2005 Apr; 3(1):1. PMID: 15807894
BACKGROUND: There is a substantial clinical overlap between chronic renal failure (CRF) and hypothyroidism, suggesting the presence of hypothyroidism in uremic patients. Although CRF patients have low T3 and T4...
6.
The evolution of drug-activated nuclear receptors: one ancestral gene diverged into two xenosensor genes in mammals
Handschin C, Blattler S, Roth A, Looser R, Oscarson M, Kaufmann M, et al.
Nucl Recept . 2004 Oct; 2(1):7. PMID: 15479477
BACKGROUND: Drugs and other xenobiotics alter gene expression of cytochromes P450 (CYP) by activating the pregnane X receptor (PXR) and constitutive androstane receptor (CAR) in mammals. In non-mammalian species, only...
7.
Diurnal difference in CAR mRNA expression
Kanno Y, Otsuka S, Hiromasa T, Nakahama T, Inouye Y
Nucl Recept . 2004 Aug; 2(1):6. PMID: 15333129
BACKGROUND: The constitutive androstane receptor (CAR, NR1I3) plays a key role in the transcriptional activation of genes that encode xenobiotic/steroid and drug metabolizing enzymes. RESULTS: The expression of CAR mRNA...
8.
Binding of estrogen receptor with estrogen conjugated to bovine serum albumin (BSA)
Taguchi Y, Koslowski M, Bodenner D
Nucl Recept . 2004 Aug; 2(1):5. PMID: 15318942
BACKGROUND: The classic model of estrogen action requires that the estrogen receptor (ER) activates gene expression by binding directly or indirectly to DNA. Recent studies, however, strongly suggest that ER...
9.
Endotoxin leads to rapid subcellular re-localization of hepatic RXRalpha: A novel mechanism for reduced hepatic gene expression in inflammation
Ghose R, Zimmerman T, Thevananther S, Karpen S
Nucl Recept . 2004 Aug; 2(1):4. PMID: 15312234
BACKGROUND: Lipopolysaccharide (LPS) treatment of animals down-regulates the expression of hepatic genes involved in a broad variety of physiological processes, collectively known as the negative hepatic acute phase response (APR)....
10.
Estrogen receptor-dependent activation of AP-1 via non-genomic signalling
Bjornstrom L, Sjoberg M
Nucl Recept . 2004 Jun; 2(1):3. PMID: 15196329
BACKGROUND: Ligand-bound estrogen receptor alpha (ERalpha) and estrogen receptor beta (ERbeta) modulate AP-1-dependent transcription via protein-protein interactions on DNA, in a manner that depends on the type of cells and...