Human Gene Therapy
Overview
Human Gene Therapy is a renowned scientific journal that focuses on cutting-edge research and advancements in the field of gene therapy. It covers a wide range of topics, including gene delivery systems, clinical trials, gene editing technologies, and therapeutic applications. With its rigorous peer-review process, the journal serves as a valuable resource for scientists, clinicians, and researchers interested in the latest developments and potential of gene therapy for treating various genetic disorders and diseases.
Details
Details
Abbr.
Hum Gene Ther
Start
1990
End
Continuing
Frequency
Twelve no. a year, 2004-
p-ISSN
1043-0342
e-ISSN
1557-7422
Country
United States
Language
English
Specialties
Pharmacology
Genetics
Genetics
Metrics
Metrics
h-index / Ranks: 1255
159
SJR / Ranks: 3270
1091
CiteScore / Ranks: 2894
7.00
JIF / Ranks: 2095
4.2
Recent Articles
11.
Chaugule S, Constantinou C, John A, Micha D, Eekhoff M, Gravallese E, et al.
Hum Gene Ther
. 2025 Feb;
36(5-6):597-617.
PMID: 39932815
Osteogenesis imperfecta (OI) is a rare genetic disorder characterized by bone fragility due to reduced bone quality, often accompanied by low bone mass, recurrent fractures, hearing loss, skeletal abnormalities, and...
12.
13.
Huttermann L, Schroder L, Shetty P, Jonker T, Hille S, Kliesow Remes A, et al.
Hum Gene Ther
. 2025 Jan;
36(3-4):101-115.
PMID: 39850991
Adeno-associated viral (AAV) vectors are increasingly used for preclinical and clinical cardiac gene therapy approaches. However, gene transfer to cardiomyocytes poses a challenge due to differences between AAV serotypes in...
14.
Laforet G
Hum Gene Ther
. 2025 Jan;
36(3-4):64-76.
PMID: 39817875
Complement-mediated thrombotic microangiopathy (TMA) in the form of atypical hemolytic uremic syndrome (aHUS) has emerged as an immune complication of systemic adeno-associated virus (AAV) gene transfer that was unforeseen based...
15.
Yuan F, Sun X, Park S, Tang Y, Feng Z, Ebadi M, et al.
Hum Gene Ther
. 2025 Jan;
PMID: 39791230
Cystic fibrosis (CF) is caused by mutations in the (). While gene therapy holds promise as a cure, the cell-type-specific heterogeneity of expression in the lung presents significant challenges. Current...
16.
Deng Z, Lv Y, Wang X, Yuan L, Zhao K, Du Z, et al.
Hum Gene Ther
. 2025 Jan;
36(3-4):116-127.
PMID: 39761134
Adeno-associated virus (AAV)-associated gene therapy has been increasingly promising, in light of the drugs progressed to clinical trials or approved for medications internationally. Therefore, scalable and efficient production of recombinant...
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19.
Sondhi D, Kaminsky S, Rosenberg J, Rostami M, Hackett N, Crystal R
Hum Gene Ther
. 2025 Jan;
36(1-2):28-35.
PMID: 39745261
CLN2 disease (late infantile neuronal ceroid lipofuscinosis) is an autosomal recessive, neurodegenerative lysosomal storage disease that results from loss of function mutations in the gene, which encodes tripeptidyl peptidase 1....
20.
Gioulvanidou M, Sarklioglu S, Chen X, Lebedeva I, Inalman Y, Pohl M, et al.
Hum Gene Ther
. 2024 Dec;
36(1-2):11-27.
PMID: 39725494
Chronic hypereosinophilia, defined as persistent elevated blood levels of eosinophils ≥1,500/μL, is associated with tissue infiltration of eosinophils and consequent organ damage by eosinophil release of toxic mediators. The current...