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Human Cell

Human Cell is a scientific journal, published by Springer since 1988 in English. The journal's country of origin is Japan and its primary focus area is cell biology.
Details
Abbr. Hum Cell
Publisher Springer
Start 1988
End Continuing
Frequency Quarterly
p-ISSN 0914-7470
e-ISSN 1749-0774
Country Japan
Language English
Specialty Cell Biology
Metrics
h-index / Ranks: 8115 44
SJR / Ranks: 5229 805
CiteScore / Ranks: 3928 5.90
JIF / Ranks: 2027 4.3
Recent Articles
1.
Derivation of functional neurons from induced pluripotent stem cells using a simple neuromesodermal progenitor generation and rapid spinal cord neuron differentiation process
Senkal-Turhan S, Bulut-Okumus E, Sahin F, Yavuz Y, Yilmaz B, Sisli H, et al.
Hum Cell . 2025 Mar; 38(3):69. PMID: 40080267
To generate spinal cord neurons from pluripotent stem cells via neuromesodermal progenitors (NMPs) is not only an important step for regenerative purposes but also required for human developmental research. This...
2.
In vitro generation of spiral ganglion neurons from embryonic stem cells
Agboola O, Deng M, Hu Z
Hum Cell . 2025 Mar; 38(3):68. PMID: 40069509
Spiral ganglion neurons (SGNs) are crucial for transmitting auditory signals from the inner ear to the brainstem, playing a pivotal role in the peripheral hearing process. However, SGNs are usually...
3.
Circ_0090100 induces AHNAK expression to inhibit trophoblast cell proliferation and invasion and accelerate cell apoptosis by segregating miR-139-5p in preeclampsia
Shan Z, Zhou L, Ma Y, Huang Y
Hum Cell . 2025 Mar; 38(3):67. PMID: 40063163
The etiology of preeclampsia (PE) is complex and is known to involve the expression of circular RNAs (circRNAs). Among these, the function of circ_0090100 in PE is yet to be...
4.
STX1A regulates ferroptosis and chemoresistance in gastric cancer through mitochondrial function modulation
Niu Y, Liu C, Jia L, Zhao F, Wang Y, Wang L, et al.
Hum Cell . 2025 Mar; 38(3):66. PMID: 40056239
Gastric cancer is one of the leading causes of cancer-related deaths worldwide, and chemoresistance remains a major obstacle to effective treatment. Ferroptosis, a novel form of regulated cell death, has...
5.
Replication factor C4, which is regulated by insulin-like growth factor 2 mRNA binding protein 2, enhances the radioresistance of breast cancer by promoting the stemness of tumor cells
Zhu X, Li P, Qu H, Ai X, Zhao Z, He J
Hum Cell . 2025 Mar; 38(3):65. PMID: 40053279
Radiotherapy resistance, is usually caused by enhanced tumor stemness and poses a significant challenge in treating breast cancer (BRCA). In this study, we investigated the molecular regulatory mechanism of radiotherapy...
6.
Novel CRISPR-Cas9 iPSC knockouts for PCCA and PCCB genes: advancing propionic acidemia research
Garcia-Tenorio E, Alvarez M, Gallego-Bonhomme M, Desviat L, Richard E
Hum Cell . 2025 Mar; 38(3):64. PMID: 40044943
Propionic acidemia (PA) is a rare autosomal recessive metabolic disorder caused by mutations in the PCCA and PCCB genes, which encode subunits of the mitochondrial enzyme propionyl-CoA carboxylase (PCC). This...
7.
Poly(I:C) signaling induces robust CXCL10 production and apoptosis in human esophageal squamous cell carcinoma cells
Sato Y, Yamaya A, Sonoda K, Wakita A, Nagaki Y, Sasamori R, et al.
Hum Cell . 2025 Mar; 38(3):63. PMID: 40029556
We previously reported that high tumoral expression of Toll-like receptor 3 (TLR3) and CXCL10, a member of the CXC chemokine family, was an independent positive prognostic factor in patients with...
8.
MTHFD2 stabilizes LOX expression through RNA methylation modification to promote sepsis-induced acute kidney injury progression
Sun S, Han B, Ren G, Fan L, Sun J, Li H, et al.
Hum Cell . 2025 Feb; 38(2):62. PMID: 40009304
Myofibroblasts combine features of fibroblasts and smooth muscle cells, and they are reactive cells present under injury conditions. This study was performed to explore the mechanism that methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2...
9.
CircTBCK protects against osteoarthritis by regulating extracellular matrix and autophagy
Wang W, Sun Y, Tang P, Zhang R, Jiang Y, Min H, et al.
Hum Cell . 2025 Feb; 38(2):60. PMID: 39998739
Osteoarthritis (OA) is a widespread chronic bone and joint disease for which there is currently no effective preventive or therapeutic treatment. Accumulating evidence indicates that circular RNAs (circRNAs), a class...
10.
Fetal adnexa-derived allogeneic mesenchymal stem cells for cardiac regeneration: the future trend of cell-based therapy for age-related adverse conditions
Gorjipour F, Bohloolighashghaei S, Sotoudeheian M, Pazoki Toroudi H
Hum Cell . 2025 Feb; 38(2):61. PMID: 39998714
Heart failure is known as the leading cause of mortality and morbidity in adults, not only in USA but worldwide. Since the world's population is aging, the burden of cardiovascular...