Zuo-Zhong Wang
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Explore the profile of Zuo-Zhong Wang including associated specialties, affiliations and a list of published articles.
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10
Citations
418
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Recent Articles
1.
Tseng C, Zhang L, Wu S, Wang W, Wang Z, Cascio M
J Biol Chem
. 2010 Jun;
285(36):27641-51.
PMID: 20566625
Agrin isoforms with different bioactivities are synthesized by the nerve and the muscle. Neural agrin containing an 8-amino acid insert (z8) introduced by alternative splicing is the active form that...
2.
Wang Y, Yao Y, Tang X, Wang Z
J Neurosci
. 2009 Oct;
29(40):12625-35.
PMID: 19812337
RIC-3 (resistant to inhibitor of cholinesterase) is a transmembrane protein, found in invertebrates and vertebrates, that modulates the surface expression of a variety of nicotinic acetylcholine receptors (nAChRs) in neurons...
3.
Linnoila J, Wang Y, Yao Y, Wang Z
Neuron
. 2008 Nov;
60(4):625-41.
PMID: 19038220
Motoneuron-derived agrin clusters nicotinic acetylcholine receptors (AChRs) in mammalian muscle cells. We used two-hybrid screens to identify a protein, tumorous imaginal discs (Tid1), that binds to the cytoplasmic domain of...
4.
Dellisanti C, Yao Y, Stroud J, Wang Z, Chen L
Channels (Austin)
. 2008 Aug;
1(4):234-7.
PMID: 18708746
Neurotoxins from snake venoms act as potent antagonists on the nicotinic acetylcholine receptors (nAChRs). Alpha-neurotoxins such as alpha-bungarotoxin (alpha-Btx) selectively bind to the skeletal muscle nAChRs among other subtypes, causing...
5.
Dellisanti C, Yao Y, Stroud J, Wang Z, Chen L
Nat Neurosci
. 2007 Jul;
10(8):953-62.
PMID: 17643119
We determined the crystal structure of the extracellular domain of the mouse nicotinic acetylcholine receptor (nAChR) alpha1 subunit bound to alpha-bungarotoxin at 1.94 A resolution. This structure is the first...
6.
Wang J, Jing Z, Zhang L, Zhou G, Braun J, Yao Y, et al.
Nat Neurosci
. 2003 Sep;
6(10):1017-8.
PMID: 14502292
At the developing neuromuscular junction, motor neuron-derived agrin triggers the differentiation of postsynaptic membrane into a highly specialized structure, where the nicotinic acetylcholine receptors (AChRs) are aggregated into high-density clusters....
7.
Wang Z, Washabaugh C, Yao Y, Wang J, Zhang L, Ontell M, et al.
J Neurosci
. 2003 Jul;
23(12):5161-9.
PMID: 12832540
Myogenic regulatory factors (MRFs), muscle-specific transcription factors, are implicated in the activity-dependent regulation of nicotinic acetylcholine receptor (AChR) subunit genes. Here we show, with immunohistochemistry, Western blotting, and electron microscopy...
8.
Tseng C, Zhang L, Cascio M, Wang Z
J Biol Chem
. 2003 Mar;
278(19):17236-45.
PMID: 12621054
Neural agrin, an extracellular matrix protein secreted by motor neurons, plays a key role in clustering of nicotinic acetylcholine receptors (AChR) on postsynaptic membranes of the neuromuscular junction. The action...
9.
Wang J, Zhang L, Yao Y, Viroonchatapan N, Rothe E, Wang Z
Nat Neurosci
. 2002 Sep;
5(10):963-70.
PMID: 12219096
Surface expression of the nicotinic acetylcholine receptor (AChR) requires the assembly of multiple subunits in the endoplasmic reticulum (ER). Little is known, however, about the mechanism by which assembled receptor...
10.
Yao Y, Wang J, Viroonchatapan N, Samson A, Chill J, Rothe E, et al.
J Biol Chem
. 2002 Jan;
277(15):12613-21.
PMID: 11812776
The alpha subunit of the nicotinic acetylcholine receptor (AChR) from Torpedo electric organ and mammalian muscle contains high affinity binding sites for alpha-bungarotoxin and for autoimmune antibodies in sera of...