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Zong-yang Li

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Articles 29
Citations 285
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Recent Articles
11.
Huang G, Chen F, Ma G, Li W, Zheng Y, Meng X, et al.
Phytomedicine . 2021 Feb; 82:153434. PMID: 33529962
Background: Glioblastoma multiforme (GBM) is the most frequent, lethal and aggressive tumour of the central nervous system in adults. The discovery of novel anti-GBM agents based on the isocitrate dehydrogenase...
12.
Chen L, Liu Y, Zheng Y, Xu J, Zhang Y, Liu W, et al.
Phytother Res . 2019 Apr; 33(6):1736-1747. PMID: 31006910
Glioblastoma multiforme (GBM) is a highly aggressive type of brain tumour. Patients with GBM respond poorly to chemotherapy and have poor survival outcomes. Neuron-glial antigen 2 (NG2), also known as...
13.
Chen L, Liu Y, Tan H, Zhang Y, Xu J, Liu W, et al.
Front Cell Neurosci . 2019 Mar; 13:61. PMID: 30886573
Aggregated amyloid-β protein (Aβ) and Aβ-induced neuronal apoptosis have been implicated as critical factors in the pathophysiology of Alzheimer's disease (AD). Certain preclinical results have indicated that the increased accumulation...
14.
Wang C, Zhao C, He Y, Li Z, Liu W, Huang X, et al.
Brain Behav . 2019 Mar; 9(4):e01248. PMID: 30834702
Background: Mild hypothermia is wildly used in clinical treatment of traumatic brain injury (TBI). However, the effect of mild hypothermia on endoplasmic reticulum (ER) stress-induced apoptosis after severe TBI is...
15.
Li Z, Huang G, Chen L, Zhang C, Chen B, Li Q, et al.
Mol Med Rep . 2017 Aug; 16(5):5908-5914. PMID: 28849207
A strategy to suppress the expression of the DNA repair enzyme O6‑methylguanine‑DNA methyltransferase (MGMT) by inhibition of Wnt/β‑catenin signaling may be useful as a novel treatment for pituitary adenoma. Previous...
16.
Li Z, Zhang C, Chen L, Chen B, Li Q, Zhang X, et al.
Phytother Res . 2017 Feb; 31(5):729-739. PMID: 28240396
Glioblastoma multiforme (GBM) is the most frequent, lethal and aggressive tumour of the central nervous system (CNS) in adults. Multidrug resistance (MDR) results in undesirable prognosis during GBM chemotherapy. In...
17.
Li Z, Zhang C, Zhang Y, Chen L, Chen B, Li Q, et al.
Cancer Lett . 2017 Jan; 391:89-99. PMID: 28131906
Temozolomide (TMZ) is the cornerstone of therapy for glioblastoma multiforme (GBM). However, its efficacy is limited due to the development of multidrug resistance (MDR). In this study, we first identified...
18.
Xu L, Chen L, Li F, Zhang R, Li Z, Chen F, et al.
J Exp Clin Cancer Res . 2016 Oct; 35(1):162. PMID: 27733185
Background: Gliomas are the most common type of primary brain tumour in the central nervous system of adults. The long non-coding RNA (lncRNA) HOXA transcript at the distal tip (HOTTIP)...
19.
Li Z, Li Q, Chen L, Chen B, Wang B, Zhang X, et al.
Neurochem Res . 2016 Sep; 41(12):3192-3205. PMID: 27632183
Glioblastoma (GBM) is the most frequent and aggressive tumour in the central nervous system. Many studies have demonstrated that upregulation of the NF-κB onco-pathway is accompanied by the acquisition of...
20.
Li Z, Li Q, Ma G, Chen L, Zhang C, Chen B, et al.
J Asian Nat Prod Res . 2016 Sep; 19(5):423-435. PMID: 27588605
Plant-derived natural products have been the highly significant sources of novel antitumor agents. The cassane-type diterpenes of genus Caesalpinia have been reported to bear antiproliferative activities toward different types of...