Zong-Kang Zhang
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Explore the profile of Zong-Kang Zhang including associated specialties, affiliations and a list of published articles.
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19
Citations
683
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Recent Articles
1.
Li X, Xu J, Yao S, Zhang N, Zhang B, Zhang Z
J Cachexia Sarcopenia Muscle
. 2025 Feb;
16(1):e13691.
PMID: 39910928
The skeletal muscle is one of the largest organs in the body and is responsible for the mechanical activity required for posture, movement and breathing. The effects of current pharmaceutical...
2.
Zhang Z, Guan D, Xu J, Li X, Zhang N, Yao S, et al.
Int J Mol Sci
. 2024 Nov;
25(22).
PMID: 39596542
Lowered muscle regenerative capacity in the elderly greatly contributes to the development of multiple diseases. The specific roles of long noncoding RNAs (lncRNAs) in muscle regenerative capacity during aging remain...
3.
Wang L, Yu Y, Ni S, Li D, Liu J, Xie D, et al.
Theranostics
. 2022 Aug;
12(13):5645-5674.
PMID: 35966595
Sclerostin inhibition demonstrated bone anabolic potential in osteogenesis imperfecta (OI) mice, whereas humanized therapeutic sclerostin antibody romosozumab for postmenopausal osteoporosis imposed clinically severe cardiac ischemic events. Therefore, it is desirable...
4.
Yu Y, Wang L, Ni S, Li D, Liu J, Chu H, et al.
Nat Commun
. 2022 Jul;
13(1):4241.
PMID: 35869074
Sclerostin negatively regulates bone formation by antagonizing Wnt signalling. An antibody targeting sclerostin for the treatment of postmenopausal osteoporosis was approved by the U.S. Food and Drug Administration, with a...
5.
Chu H, Chen Z, Wang L, Zhang Z, Tan X, Liu S, et al.
Front Immunol
. 2021 Jun;
12:658097.
PMID: 34093545
Clinical studies in a range of cancers have detected elevated levels of the Wnt antagonist Dickkopf-1 (DKK1) in the serum or tumors of patients, and this was frequently associated with...
6.
Zhang N, Chen Z, Liu D, Jiang H, Zhang Z, Lu A, et al.
Int J Mol Sci
. 2021 Apr;
22(8).
PMID: 33920991
Aptamers are promising therapeutic and diagnostic agents for various diseases due to their high affinity and specificity against target proteins. Structural determination in combination with multiple biochemical and biophysical methods...
7.
Chen Z, Zhang N, Chu H, Yu Y, Zhang Z, Zhang G, et al.
Front Cell Dev Biol
. 2020 Nov;
8:593269.
PMID: 33195264
Connective tissue growth factor (CTGF) is a key signaling and regulatory molecule involved in different biological processes, such as cell proliferation, angiogenesis, and wound healing, as well as multiple pathologies,...
8.
Zhang N, Zhang Z, Yu Y, Zhuo Z, Zhang G, Zhang B
Front Cell Dev Biol
. 2020 Jun;
8:325.
PMID: 32478071
Osteoporosis is age-related deterioration in bone mass and micro-architecture. Denosumab is a novel human monoclonal antibody for osteoporosis. It is a receptor activator of nuclear factor-κB ligand (RANKL) inhibitor, which...
9.
Zheng Y, Wang X, Zhang Z, Guo B, Dang L, He B, et al.
Sci Rep
. 2019 Feb;
9(1):2089.
PMID: 30765762
Falls in late postmenopausal women with osteopenia usually cause fractures with severe consequences. This 36-month randomized, double-blind and placebo-controlled trial with a 10-year observational follow-up study aimed to investigate the...
10.
Zhang Z, Li J, Guan D, Liang C, Zhuo Z, Liu J, et al.
Mol Ther
. 2018 Nov;
26(11):2669-2680.
PMID: 30415659
Reversing established muscle atrophy following mechanical unloading is of great clinical challenge. Long noncoding RNAs (lncRNAs) have been demonstrated to play important roles in myogenesis. Here we identified a lncRNA...