Zohreh Khavandgar
Overview
Explore the profile of Zohreh Khavandgar including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
202
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Recent Articles
11.
Khavandgar Z, Murshed M
Cell Mol Life Sci
. 2014 Nov;
72(5):959-69.
PMID: 25424644
The regulators affecting skeletal tissue formation and its maintenance include a wide array of molecules with very diverse functions. More recently, sphingolipids have been added to this growing list of...
12.
Tabatabaei N, Rodd C, Kremer R, Khavandgar Z, Murshed M, Weiler H
J Nutr
. 2014 Oct;
144(12):1985-93.
PMID: 25320192
Background: The effects of vitamin D during pregnancy on maternal and neonatal bone health remain unclear. Objective: This study was designed to test whether dietary vitamin D dose-dependently affects maternal...
13.
Li Z, Wu G, Sher R, Khavandgar Z, Hermansson M, Cox G, et al.
Biochim Biophys Acta
. 2014 Mar;
1840(7):2112-22.
PMID: 24637075
Background: Choline kinase has three isoforms encoded by the genes Chka and Chkb. Inactivation of Chka in mice results in embryonic lethality, whereas Chkb(-/-) mice display neonatal forelimb bone deformations....
14.
Alebrahim S, Khavandgar Z, Marulanda J, Murshed M
Genesis
. 2014 Mar;
52(5):408-16.
PMID: 24585429
Sphingomyelin phosphodiesterase 3 (SMPD3) is a pleiotropic lipid metabolizing enzyme involved in multiple physiological processes. A deletion mutation in the murine Smpd3 gene called fragilitas ossium (fro) leads to severe...
15.
Khavandgar Z, Roman H, Li J, Lee S, Vali H, Brinckmann J, et al.
J Bone Miner Res
. 2013 Jul;
29(2):327-37.
PMID: 23857752
Matrix gla protein (MGP) is a potent inhibitor of extracellular matrix (ECM) mineralization. MGP-deficiency in humans leads to Keutel syndrome, a rare genetic disease hallmarked by abnormal soft tissue calcification....
16.
Meyers-Needham M, Lewis J, Gencer S, Sentelle R, Saddoughi S, Clarke C, et al.
Mol Cancer Ther
. 2012 Mar;
11(5):1092-102.
PMID: 22452947
Sonic hedgehog (SHh) signaling is important in the pathogenesis of various human cancers, such as medulloblastomas, and it has been identified as a valid target for anticancer therapeutics. The SHh...
17.
Khavandgar Z, Poirier C, Clarke C, Li J, Wang N, McKee M, et al.
J Cell Biol
. 2011 Jul;
194(2):277-89.
PMID: 21788370
A deletion mutation called fro (fragilitas ossium) in the murine Smpd3 (sphingomyelin phosphodiesterase 3) gene leads to a severe skeletal dysplasia. Smpd3 encodes a neutral sphingomyelinase (nSMase2), which cleaves sphingomyelin...
18.
Li J, Khavandgar Z, Lin S, Murshed M
Bone
. 2010 Oct;
48(2):321-31.
PMID: 20932949
Lithium inhibition of glycogen synthase kinase3 (GSK3) activity has been shown to mimic the canonical WNT signaling. Analogous to WNT, lithium prevents GSK3-mediated phosphorylation of cytosolic transcription factor β-catenin and...