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Zhonghui Tang

Explore the profile of Zhonghui Tang including associated specialties, affiliations and a list of published articles. Areas
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Articles 32
Citations 2559
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Recent Articles
1.
Ke H, Li P, Li Z, Zeng X, Zhang C, Luo S, et al.
Clin Transl Med . 2025 Feb; 15(2):e70175. PMID: 39934971
Background: Tumour immune macroenvironment is comprised of tumour and surrounding organs responding to tumourigenesis and immunotherapy. The lack of comprehensive analytical methods hinders its application for prediction of survival and...
2.
Zhang Y, Li H, Breed M, Tang Z, Cui L, Zhu Y, et al.
Microbiome . 2025 Feb; 13(1):42. PMID: 39915809
Background: Global warming is redrawing the map for invasive species, spotlighting the globally harmful giant African snail as a major ecological disruptor and public health threat. Known for harboring extensive...
3.
Liu Q, Dong W, Liu R, Xu L, Ran L, Xie Z, et al.
Protein Cell . 2025 Jan; PMID: 39804040
Extensive epigenetic reprogramming involves in memory CD8+ T-cell differentiation. The elaborate epigenetic rewiring underlying the heterogeneous functional states of CD8+ T cells remains hidden. Here, we profile single-cell chromatin accessibility...
4.
Zhu R, Ye X, Lu X, Xiao L, Yuan M, Zhao H, et al.
Cell Metab . 2024 Nov; 37(2):361-376.e7. PMID: 39561764
Lactyl-coenzyme A (CoA)-dependent histone lysine lactylation impacts gene expression and plays fundamental roles in biological processes. However, mammalian lactyl-CoA synthetases and their regulation of histone lactylation have not yet been...
5.
Sun W, Xiong D, Ouyang J, Xiao X, Jiang Y, Wang Y, et al.
Nat Commun . 2024 Jun; 15(1):5048. PMID: 38871723
Despite the advent of genomic sequencing, molecular diagnosis remains unsolved in approximately half of patients with Mendelian disorders, largely due to unclarified functions of noncoding regions and the difficulty in...
6.
Tian Y, Wu X, Luo S, Xiong D, Liu R, Hu L, et al.
Comput Struct Biotechnol J . 2024 Jun; 23:2173-2189. PMID: 38827229
The vast neuronal diversity in the human neocortex is vital for high-order brain functions, necessitating elucidation of the regulatory mechanisms underlying such unparalleled diversity. However, recent studies have yet to...
7.
Liang Y, Shi G, Cai R, Yuan Y, Xie Z, Yu L, et al.
Nat Commun . 2024 Jan; 15(1):600. PMID: 38238417
Computational methods have been proposed to leverage spatially resolved transcriptomic data, pinpointing genes with spatial expression patterns and delineating tissue domains. However, existing approaches fall short in uniformly quantifying spatially...
8.
Liu R, Dong W, Xiong D, Hu L, Zhang H, Yuan X, et al.
Front Neurosci . 2023 Jul; 17:1177747. PMID: 37449269
Introduction: Cortical neural progenitor cells possess the capacity to differentiate into both excitatory and inhibitory neurons. However, the precise proportions in which these progenitor cells differentiate remain unclear. Methods: Human...
9.
Wang C, Liu X, Liang J, Narita Y, Ding W, Li D, et al.
Nat Commun . 2023 Mar; 14(1):1598. PMID: 36949074
Epstein-Barr virus (EBV) immortalization of resting B lymphocytes (RBLs) to lymphoblastoid cell lines (LCLs) models human DNA tumor virus oncogenesis. RBL and LCL chromatin interaction maps are compared to identify...
10.
Dong W, Li W, Zhang S, Zeng X, Qin Q, Fan H, et al.
Int J Mol Med . 2023 Feb; 51(3). PMID: 36799159
Maternal engraftment is frequently present in X‑linked severe combined immunodeficiency (X‑SCID) patients caused by pathogenic mutations in . However, the functional status of the engrafted cells remains unclear because of...