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Zhenhua Ding

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Articles 56
Citations 756
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Recent Articles
1.
Jin Y, Fu J, Jiang C, Ding Z
J Org Chem . 2025 Mar; PMID: 40080862
Bicyclo[3.2.1]octanes widely exist in natural products and bioactive compounds. However, the efficient construction of these skeletons remains a challenge. Herein, we reported a convenient synthesis of diaza-oxabicyclo[3.2.1]octanes and dioxa-azabicyclo[3.2.1]octanes by...
2.
Liu S, Fu Z, Liu H, Wang Y, Zhou M, Ding Z, et al.
Biomedicines . 2025 Jan; 13(1). PMID: 39857597
The relationship between lipid profiles, telomere length (TL), and cancer risk remains unclear. This study employed two-sample Mendelian randomization (MR) with mediation analysis to investigate their causal relationships, examining lipid...
3.
Chen J, Jin Y, Fu J, Jiang C, Ding Z
J Org Chem . 2024 Oct; 89(21):15884-15892. PMID: 39412824
Bicyclo[3.2.1]octane (BCO) skeleton widely exists in natural products and biologically active molecules, whereas the development of convenient approaches to construct this structure remains a challenge. Herein, we describe a cascade...
4.
Du J, Chen F, Du C, Zhao W, Chen Z, Ding Z, et al.
Cell Death Discov . 2024 Oct; 10(1):434. PMID: 39394181
DNA damage is considered to be a potentially unifying driver of ageing, and the stalling of DNA damage repair accelerates the cellular senescence. However, augmenting DNA repair has remained a...
5.
Zhang Y, Xie J, Zhang H, Li J, Mi X, Zhou X, et al.
Arch Biochem Biophys . 2024 Sep; 761:110138. PMID: 39303929
Introduction: Local exposure to ionizing radiation (IR) can induce changes in biological processes in distant tissues and organs. Exosomes are nanoscale vesicles that transport biomolecules, mediate communication between cells and...
6.
Farooq A, Yang H, Ding Z, Bu F, Guo M, Sun W, et al.
Int J Biol Macromol . 2024 Jul; 275(Pt 2):133629. PMID: 38964682
In this study, we investigated the use of deep eutectic solvents (DESs) at different molar ratios and temperatures as a green and efficient approach for microfibers (MFs) extraction. Our approach...
7.
Wang Y, Deng X, Xie J, Lu T, Qian R, Guo Z, et al.
Cell Biol Toxicol . 2024 Jun; 40(1):45. PMID: 38864940
MALT1 has been implicated as an upstream regulator of NF-κB signaling in immune cells and tumors. This study determined the regulatory mechanisms and biological functions of MALT1 in non-small cell...
8.
Niu X, Shen Y, Wen Y, Mi X, Xie J, Zhang Y, et al.
J Dermatol Sci . 2024 Mar; 114(1):24-33. PMID: 38448340
Background: The unfolded protein response (UPR) is one of the cytoprotective mechanisms against various stresses and essential for the normal function of skin. Skin injury caused by ionizing radiation (IR)...
9.
Zhang Q, Zhou Z, Fan Y, Liu T, Guo Y, Li X, et al.
Microbiol Spectr . 2023 Nov; 12(1):e0109023. PMID: 38018973
HAdV-3, -7, and -55 are the predominant types causing acute respiratory disease outbreaks and can lead to severe and fatal pneumonia in children and adults. In recent years, emerging or...
10.
Sun M, Chen J, Ding Z
J Org Chem . 2023 Jul; 88(15):10647-10654. PMID: 37470361
A new approach to oxazolidines and dihydroxazines was developed by regioselective cyclization of α-aminated ketones under transition metal-free conditions. Oxazolidine derivatives were generated in the presence of chloro benziodoxole and...