Zhengsheng Chen
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Explore the profile of Zhengsheng Chen including associated specialties, affiliations and a list of published articles.
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9
Citations
33
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Recent Articles
1.
Feng K, Liu J, Gong L, Ye T, Chen Z, Wang Y, et al.
Adv Sci (Weinh)
. 2025 Jan;
12(8):e2413759.
PMID: 39755936
Chondrocyte senescence is an important pathogenic factor causing osteoarthritis (OA) progression through persistently producing pro-inflammatory factors. Mesenchymal stem cells-derived small extracellular vesicles (MSC-sEVs) have shown anti-inflammatory effects in OA models,...
2.
Feng K, Ye T, Xie X, Liu J, Gong L, Chen Z, et al.
Pharmacol Res
. 2024 Oct;
209:107474.
PMID: 39433168
Osteoarthritis (OA) is a common joint degenerative disease which currently lacks satisfactory disease-modifying treatments. Oxidative stress-mediated senescent chondrocytes accumulation is closely associated with OA progression, which abrogates cartilage metabolism homeostasis...
3.
Huang Z, Chen Z, Ye T, Luo L, Zhang J, Li Q, et al.
Nanomedicine (Lond)
. 2024 Jul;
19(17):1525-1539.
PMID: 39012207
This study aims to investigate the effects of large extracellular vesicles (EVs) induced by pluripotent stem cell-derived mesenchymal stem cells on lower limb ischemic disease and explore its potential mechanisms....
4.
Gong L, Chen Z, Feng K, Luo L, Zhang J, Yuan J, et al.
J Nanobiotechnology
. 2024 Mar;
22(1):105.
PMID: 38468249
Chemotherapy is an important therapeutic approach for malignant tumors for it triggers apoptosis of cancer cells. However, chemotherapy also induces senescence of stromal cells in the tumor microenvironment to promote...
5.
Chen Z, Luo L, Ye T, Zhou J, Niu X, Yuan J, et al.
J Extracell Vesicles
. 2024 Feb;
13(2):e12409.
PMID: 38321535
Pluripotent stem cell-derived small extracellular vesicles (PSC-sEVs) have demonstrated great clinical translational potential in multiple aging-related degenerative diseases. Characterizing the PSC-sEVs is crucial for their clinical applications. However, the specific...
6.
Feng K, Yu Y, Chen Z, Wang F, Zhang K, Chen H, et al.
Mater Today Bio
. 2023 May;
20:100637.
PMID: 37128287
Osteoarthritis (OA) is the most common age-related degenerative joint disease mainly characterized by the destruction of articular cartilage. Owing to its native avascular property, intrinsic repair of articular cartilage is...
7.
Ye T, Chen Z, Zhang J, Luo L, Gao R, Gong L, et al.
Bioact Mater
. 2022 Sep;
21:194-208.
PMID: 36101856
Tendinopathy is a common musculoskeletal disorder which results in chronic pain and reduced performance. The therapeutic effect of stem cell derived-small extracellular vesicles (sEVs) for tendinopathy has been validated in...
8.
Guo J, Qian Y, Sun B, Sun Z, Chen Z, Mao H, et al.
ACS Appl Bio Mater
. 2022 Jan;
2(10):4418-4426.
PMID: 35021401
Bacteria induced infection remains a serious medical hazard to humans. Antibacterial polymeric materials, which can kill or inhibit bacteria by disrupting cell membranes, inhibiting certain enzymes, or interfering with the...
9.
Kreuzer W, Majdak P, Chen Z
J Acoust Soc Am
. 2009 Sep;
126(3):1280-90.
PMID: 19739742
Head-related transfer functions (HRTFs) play an important role in spatial sound localization. The boundary element method (BEM) can be applied to calculate HRTFs from non-contact visual scans. Because of high...