Zhengquan Lai
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Explore the profile of Zhengquan Lai including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
150
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Recent Articles
1.
Qu J, Yan Z, Lei D, Zhong T, Fang C, Wen Z, et al.
ACS Nano
. 2024 Jul;
18(29):19354-19368.
PMID: 38975953
Tumor-stromal interactions and stromal heterogeneity in the tumor microenvironment are critical factors that influence the progression, metastasis, and chemoresistance of pancreatic ductal adenocarcinoma (PDAC). Here, we used spatial transcriptome technology...
2.
Huang Z, Zhang S, Qin Z, Ai G, Li M, Gong S, et al.
Int J Nanomedicine
. 2024 Jun;
19:5297-5316.
PMID: 38859955
Propose: Oxyberberine (OBB), one of the main metabolites of berberine derived from intestinal and erythrocyte metabolism, exhibits appreciable anti-hyperuricemic activity. However, the low water solubility and poor plasma concentration-effect relationship...
3.
Zhang C, Lei D, Zhou Y, Zhong T, Li X, Ai W, et al.
Front Immunol
. 2023 Aug;
14:1223650.
PMID: 37575248
Pancreatic ductal adenocarcinoma (PDAC) is one of the most malignant and lethal human cancers in the world due to its high metastatic potential, and patients with PDAC have a poor...
4.
Zheng X, Mai L, Xu Y, Wu M, Chen L, Chen B, et al.
Front Pharmacol
. 2023 Mar;
14:1136076.
PMID: 36895947
(L.) Merr, has a long history to be an anti-dysentery medicine for thousand of years, which is commonly called "Ya-Dan-Zi" in Chinese. The common liquid preparation of its seed, oil...
5.
Yang T, You C, Meng S, Lai Z, Ai W, Zhang J
Front Cell Infect Microbiol
. 2022 Jul;
12:935205.
PMID: 35846746
Viral oncogenes may drive cellular metabolic reprogramming to modulate the normal epithelia cell malignant transformation. Understanding the viral oncogene-mediated signaling transduction dysregulation that involves in metabolic reprogramming may provide new...
6.
Su J, Chen X, Xiao Y, Li D, Li M, Li H, et al.
Front Pharmacol
. 2021 Oct;
12:727082.
PMID: 34658867
Triple-negative breast cancer (TNBC) has been acknowledged as an aggressive disease with worst prognosis, which requires endeavor to develop novel therapeutic agents. Bruceae fructus oil (BO), a vegetable oil derived...
7.
Xu L, Huang Q, Tan X, Zhao Q, Wu J, Liao H, et al.
Int Immunopharmacol
. 2021 Jun;
98:107897.
PMID: 34182243
Alcoholism represents a predisposing factor for liver-related morbidity and mortality worldwide. Pogostemon cablin has been widely used in China for the treatment of digestive system diseases. Patchouli oil, the major...
8.
Xie J, Lai Z, Zheng X, Liao H, Xian Y, Li Q, et al.
Toxicology
. 2021 Jan;
451:152680.
PMID: 33465425
Brusatol occurs as a characteristic bioactive principle of Brucea javanica (L.) Merr., a traditional medicinal herb frequently employed to tackle cancer in China. This work endeavored to unravel the potential...
9.
Chen Y, Xian Y, Loo S, Lai Z, Chan W, Liu L, et al.
J Ethnopharmacol
. 2019 Nov;
249:112367.
PMID: 31678637
Ethnopharmacological Relevance: Huang-Lian-Jie-Du Decoction (HLJDD), is a well-known traditional Chinese herbal formula first written in the Tang dynasty. In Chinese medicine practice, HLJDD is commonly prescribed to treat various inflammatory...
10.
Zhou J, Tan L, Xie J, Lai Z, Huang Y, Qu C, et al.
Drug Deliv
. 2017 Oct;
24(1):1667-1679.
PMID: 29078713
Brusatol (BR) is one of the main bioactive components derived from Brucea javanica, a medicinal herb historically used in the treatment of dysenteric disorders (also known as ulcerative colitis(UC)). Due...