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Zhengping Wei

Explore the profile of Zhengping Wei including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 288
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Recent Articles
1.
Luo Y, Li D, Xie L, Lei S, Chen X, Wang C, et al.
Front Immunol . 2022 Sep; 13:942465. PMID: 36045674
Follicular helper T (T) cells provide specialized help for B cells to ensure optimal humoral immunity. The histone methyltransferase EZH2, as a chromatin repressor, secures the T differentiation by promoting...
2.
Xia M, Zhang C, Chen Y, Zhao X, Zhang S, Liu Y, et al.
Proc Natl Acad Sci U S A . 2022 Jul; 119(31):e2205469119. PMID: 35895684
T regulatory (Treg) cells are essential for self-tolerance whereas they are detrimental for dampening the host anti-tumor immunity. How Treg cells adapt to environmental signals to orchestrate their homeostasis and...
3.
Xiao M, Xie L, Cao G, Lei S, Wang P, Wei Z, et al.
J Immunother Cancer . 2022 May; 10(5). PMID: 35580929
Background: Antitumor therapeutic vaccines are generally based on antigenic epitopes presented by major histocompatibility complex (MHC-I) molecules to induce tumor-specific CD8 T cells. Paradoxically, continuous T cell receptor (TCR) stimulation...
4.
Wang Y, Tian Q, Hao Y, Yao W, Lu J, Chen C, et al.
Nat Immunol . 2021 Dec; 23(2):303-317. PMID: 34949833
Antigen-specific memory CD4 T cells can persist and confer rapid and efficient protection from microbial reinfection. However, the mechanisms underlying the long-term maintenance of the memory CD4 T cell pool...
5.
Liu N, Feng Y, Liu H, Wu W, Liang Y, Li P, et al.
Allergy Asthma Immunol Res . 2021 Mar; 13(3):479-497. PMID: 33733641
Purpose: Macrophages are important regulators of environmental allergen-induced airway inflammation and asthma. ATP6V0d2 is a subunit of vacuolar ATPase highly expressed in macrophages. However, the functions of ATP6V0d2 in the...
6.
Wei Z, Du Q, Li P, Liu H, Xia M, Chen Y, et al.
FASEB J . 2020 Nov; 35(1):e21138. PMID: 33184932
Appropriate migration of cytotoxic T effector cells into the tumors is crucial for their antitumor function. Despite the controversial role of PI3K-Akt in CD8 T cell mTORC1 activation, a link...
7.
Wei Z, Li P, He R, Liu H, Liu N, Xia Y, et al.
Cell Mol Immunol . 2019 Sep; 18(1):138-149. PMID: 31541182
Mechanistic target of rapamycin complex 1 (mTORC1) regulates CD8 T-cell differentiation and function. Despite the links between PI3K-AKT and mTORC1 activation in CD8 T cells, the molecular mechanism underlying mTORC1...
8.
Zhang C, Duan Y, Xia M, Dong Y, Chen Y, Zheng L, et al.
Clin Cancer Res . 2019 Aug; 25(22):6827-6838. PMID: 31383732
Purpose: Despite the FDA approval of mTOR inhibitors (mTORi) for the treatment of renal cell carcinoma (RCC), the benefits are relatively modest and the few responders usually develop resistance. We...
9.
Li P, Deng X, Luo J, Chen Y, Bi G, Gong F, et al.
Protein Cell . 2019 May; 10(8):615-619. PMID: 31134526
No abstract available.
10.
Liu H, Li P, Wei Z, Zhang C, Xia M, Du Q, et al.
Semin Immunopathol . 2019 Apr; 41(3):315-326. PMID: 30963214
Peripheral naive CD4 and CD8 cells are developed in the thymus and proliferate and differentiate into various specialized T cell subsets upon activation by peptide-major histocompatibility complexes in periphery to...