Zhengfang Lu
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Explore the profile of Zhengfang Lu including associated specialties, affiliations and a list of published articles.
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15
Citations
185
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0
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Recent Articles
1.
Liu C, Zhang D, Lu Z, Man J, Zhang Z, Fu X, et al.
Neurosci Lett
. 2022 Jun;
783:136708.
PMID: 35660649
Metformin (MET) has been the subject of many classic studies in possessing antiapoptotic, anti-inflammatory, antioxidation activities and antiviral. Recently investigators have examined the anti-apoptosis effects of MET in acute myocardial...
2.
Gao Y, Fu X, Yu L, Zhang D, Lu Z, Cui K, et al.
Evid Based Complement Alternat Med
. 2021 Oct;
2021:1186458.
PMID: 34616473
Objective: Spontaneous intracerebral hemorrhage (ICH) is a blood clot arising in the brain parenchyma in the absence of trauma or surgery and accounts for 10% to 15% of all strokes,...
3.
Zhang Z, Lu Z, Liu C, Man J, Li X, Cui K, et al.
Neuroreport
. 2021 Aug;
32(14):1161-1169.
PMID: 34334775
Objectives: After ischemic stroke, microglia will be activated and play a key role in neuroinflammation and the destruction of the blood-brain barrier (BBB), and activated microglia could polarize into pro-inflammation...
4.
Man J, Cui K, Fu X, Zhang D, Lu Z, Gao Y, et al.
Brain Res
. 2020 Mar;
1736:146782.
PMID: 32184165
Donepezil, a selective acetylcholinesterase (AchE) inhibitor, enhances stroke-induced neurogenesis within subventricular zone (SVZ). Src/Pyk-2 is one of the downstream pathways of acetylcholine receptors (AchRs), and has been shown to participate...
5.
Zhang Y, Wang J, Zhang D, Lu Z, Man J
Int Immunopharmacol
. 2020 Feb;
81:106281.
PMID: 32058930
Cerebral infarction causes severe social and economic burdens to patients due to its high morbidity and mortality rates, and the available treatments are limited. RO27-3225 is a highly selective melanocortin...
6.
Lu Z, Zhang D, Cui K, Fu X, Man J, Lu H, et al.
Neuroscience
. 2019 Dec;
428:228-241.
PMID: 31887363
Teriflunomide has been reported to inhibit microglial activation in experimental models of traumatic brain injury. However, its roles in ischemic stroke and underlying mechanisms of action are still undiscovered. In...
7.
Zhang D, Lu Z, Zhang Z, Man J, Guo R, Liu C, et al.
Int Immunopharmacol
. 2019 Nov;
77:105924.
PMID: 31678864
As a membrane-permeable derivative of itaconate, dimethyl itaconate (DMI) was recently showed to limit inflammatory response of activated macrophages, and to decrease the generation of reactive oxygen species and reduce...
8.
Zhang D, Lu Z, Man J, Cui K, Fu X, Yu L, et al.
Int Immunopharmacol
. 2019 Jul;
75:105760.
PMID: 31323530
Neuroinflammation crucially influences functional recovery after ischemic stroke. Wnt-3a, a novel Wnt protein that specifically promotes Wnt/β-catenin signaling pathway, has been shown to regulate apoptosis and cell proliferation, but how...
9.
Wang J, Zhang D, Fu X, Yu L, Lu Z, Gao Y, et al.
J Neuroinflammation
. 2018 Jun;
15(1):188.
PMID: 29929562
Background: At low levels, carbon monoxide (CO) has been shown to have beneficial effects on multiple organs and tissues through its potential anti-inflammatory, anti-apoptotic, and anti-proliferative properties. However, the effect...
10.
Wang J, Fu X, Zhang D, Yu L, Lu Z, Gao Y, et al.
Neuroscience
. 2017 Sep;
364:202-211.
PMID: 28943249
Neurogenesis in the subventricular zone (SVZ) plays a vital role in neurologic recovery after stroke. However, only a small fraction of newly generated neuroblasts from the SVZ will survive long-term....