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Zhenchang Jia

Explore the profile of Zhenchang Jia including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 108
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Recent Articles
1.
Wu Q, Tian P, He D, Jia Z, He Y, Luo W, et al.
Cell Res . 2023 May; 33(6):464-478. PMID: 37142671
Estrogen receptor (ER)-positive luminal breast cancer is a subtype with generally lower risk of metastasis to most distant organs. However, bone recurrence occurs preferentially in luminal breast cancer. The mechanisms...
2.
Wang Y, Jia Z, Liang C, He Y, Cong M, Wu Q, et al.
Cell Discov . 2023 Feb; 9(1):20. PMID: 36810288
Immune checkpoint blockade (ICB) therapy targeting PD-1/PD-L1 has shown durable clinical benefits in lung cancer. However, many patients respond poorly to ICB treatment, underscoring an incomplete understanding of PD-L1 regulation...
3.
He Y, Luo W, Liu Y, Wang Y, Ma C, Wu Q, et al.
J Clin Invest . 2022 Aug; 132(20). PMID: 36006737
Bone is a common site of metastasis in lung cancer, but the regulatory mechanism remains incompletely understood. Osteoclasts are known to play crucial roles in osteolytic bone metastasis by digesting...
4.
Ma C, He D, Tian P, Wang Y, He Y, Wu Q, et al.
Proc Natl Acad Sci U S A . 2022 Feb; 119(6). PMID: 35105806
The protumor roles of alternatively activated (M2) tumor-associated macrophages (TAMs) have been well established, and macrophage reprogramming is an important therapeutic goal. However, the mechanisms of TAM polarization remain incompletely...
5.
He Y, Cheng D, Lian C, Liu Y, Luo W, Wang Y, et al.
Cell Death Dis . 2021 Sep; 12(10):868. PMID: 34556636
Giant cell tumor of bone (GCTB) is an aggressive osteolytic bone tumor characterized by the within-tumor presence of osteoclast-like multinucleated giant cells (MGCs), which are induced by the neoplastic stromal...
6.
Lin X, Chen L, Li H, Liu Y, Guan Y, Li X, et al.
Am J Physiol Gastrointest Liver Physiol . 2018 May; 315(4):G443-G453. PMID: 29792529
Liver regeneration after two-thirds partial hepatectomy (PH) is a clinically significant repair process for restoring proper liver architecture. Although microRNA-155 (miR-155) has been found to serve as a crucial microRNA...