Zhangping Xiao
Overview
Explore the profile of Zhangping Xiao including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
114
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0
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Recent Articles
1.
Xiao Z, Osipyan A, Song S, Chen D, Schut R, van Merkerk R, et al.
J Med Chem
. 2025 Mar;
PMID: 40064548
No abstract available.
2.
Zhang F, Zhao B, Fan Y, Qin L, Shi J, Chen L, et al.
Acta Pharm Sin B
. 2025 Mar;
15(1):508-525.
PMID: 40041894
The aryl hydrocarbon receptor (AhR) plays a crucial role in regulating many physiological processes. Activating the AhR-CYP1A1 axis has emerged as a novel therapeutic strategy against various inflammatory diseases. Here,...
3.
Xiao Z, Gavriil E, Cao F, Zhang X, Li S, Kotelnikov S, et al.
bioRxiv
. 2025 Feb;
PMID: 39975383
Targeted protein degradation (TPD) is a rapidly emerging and potentially transformative therapeutic modality. However, the large majority of >600 known ubiquitin ligases have yet to be exploited as TPD effectors...
4.
Chen D, Zhao C, Zhang J, Knol C, Osipyan A, Majernikova N, et al.
Adv Sci (Weinh)
. 2024 Jun;
11(32):e2403963.
PMID: 38924362
Ferroptosis is a form of regulated cell death that can be modulated by small molecules and has the potential for the development of therapeutics for oncology. Although excessive lipid peroxidation...
5.
Bakhshalizadeh S, Afkhami F, Bell K, Robevska G, van den Bergen J, Cronin S, et al.
Mol Cell Endocrinol
. 2024 Mar;
587:112212.
PMID: 38521400
Research Question: Premature ovarian insufficiency (POI) is characterised by amenorrhea associated with elevated follicle stimulating hormone (FSH) under the age of 40 years and affects 1-3.7% women. Genetic factors explain...
6.
Ritzefeld M, Zhang L, Xiao Z, Andrei S, Boyd O, Masumoto N, et al.
J Med Chem
. 2024 Jan;
67(2):1061-1078.
PMID: 38198226
Hedgehog signaling is involved in embryonic development and cancer growth. Functional activity of secreted Hedgehog signaling proteins is dependent on -terminal palmitoylation, making the palmitoyl transferase Hedgehog acyltransferase (HHAT), a...
7.
Chen D, Osipyan A, Adriana J, Kader M, Gureev M, Knol C, et al.
J Med Chem
. 2023 Jun;
66(13):8767-8781.
PMID: 37352470
Macrophage migration inhibitory factor (MIF) is a multifunctional cytokine and essential signaling protein associated with inflammation and cancers. One of the newly described roles of MIF is binding to apoptosis-inducing...
8.
Xiao Z, Gray J, Tate E
Cell Chem Biol
. 2023 May;
30(5):415-417.
PMID: 37207629
In this issue of Cell Chemical Biology, Zhan et al. report dual-pharmacophore molecules ("artezomibs"), combining an artemisinin and proteasome inhibitor that exhibit potent activity against both wild-type and drug-resistant malarial...
9.
Sun X, Yu X, Zhao Y, Xing L, Na L, Chen Z, et al.
Eur J Med Chem
. 2023 Jan;
247:115053.
PMID: 36587419
Herein 2-cyanoethoxy-N,N,N',N'-tetraisopropyl-phosphorodiamidite(10, P, 3.5 eq.) could synergistically react with 3',5'-dihydroxyl groups in a dinucleotide(P) at the cyclization step for the synthesis of cyclic dinucleotides (CDNs) (c-di-GMP, cGAMP etc.) and their...
10.
Song S, Xiao Z, Dekker F, Poelarends G, Melgert B
Cell Mol Life Sci
. 2022 Jan;
79(2):105.
PMID: 35091838
The family of macrophage migration inhibitory factor (MIF) proteins in humans consist of MIF, its functional homolog D-dopachrome tautomerase (D-DT, also known as MIF-2) and the relatively unknown protein named...