Zengli Guo
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Explore the profile of Zengli Guo including associated specialties, affiliations and a list of published articles.
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19
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347
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Recent Articles
11.
Guo Z, Wang G, Wu B, Chou W, Cheng L, Zhou C, et al.
J Clin Invest
. 2020 Jul;
130(11):5893-5908.
PMID: 32730228
As a hallmark of immunological aging, low-grade, chronic inflammation with accumulation of effector memory T cells contributes to increased susceptibility to many aging-related diseases. While the proinflammatory state of aged...
12.
Wu B, Zhang G, Guo Z, Wang G, Xu X, Li J, et al.
Cell Mol Immunol
. 2020 Jul;
18(10):2410-2421.
PMID: 32612153
Acute viral infection causes illness and death. In addition, an infection often results in increased susceptibility to a secondary infection, but the mechanisms behind this susceptibility are poorly understood. Since...
13.
Guo Z, Wang G, Lv Y, Wan Y, Zheng J
Front Immunol
. 2019 Sep;
10:1988.
PMID: 31552016
Foxp3 expressing regulatory T (Treg) cells, as the central negative regulator of adaptive immune system, are essential to suppress immune response and maintain immune homeostasis. However, the function of Treg...
14.
Wu B, Zhang S, Guo Z, Wang G, Zhang G, Xie L, et al.
Immunity
. 2018 Nov;
49(5):886-898.e5.
PMID: 30446383
Pathogenic Th17 (pTh17) cells drive inflammation and immune-pathology, but whether pTh17 cells are a Th17 cell subset whose generation is under specific molecular control remains unaddressed. We found that Ras...
15.
Wang H, Zhang C, Wang X, Lian Y, Guo B, Han M, et al.
Int J Biol Sci
. 2018 Feb;
14(1):10-20.
PMID: 29483821
Congenital anomalies of the kidney and urinary tract (CAKUT) are among the most common developmental defects in humans. Despite of several known CAKUT-related loci (, , , etc.), the genetic...
16.
Tang Z, Guo Z, Zhou L, Xue S, Zhu Q, Zhu H
Int J Environ Res Public Health
. 2016 Nov;
13(11).
PMID: 27827866
This research aims at combined and relative effect levels on anxiety of: (1) perceived risk, knowledge, optimism, pessimism, and social trust; and (2) four sub-variables of social trust among inhabitants...
17.
Guo Z, Kong Q, Liu C, Zhang S, Zou L, Yan F, et al.
Nat Commun
. 2016 Jan;
7:10307.
PMID: 26728942
On activation, naive T cells grow in size and enter cell cycle to mount immune response. How the fundamental processes of T-cell growth and cell cycle entry are regulated is...
18.
Zhao Y, Wang Y, Guo Z, Gu A, Dan H, Baldwin A, et al.
J Immunol
. 2012 Sep;
189(9):4417-25.
PMID: 22993204
Dihydroartemisinin (DHA) is an important derivative of the herb medicine Artemisia annua L., used in ancient China. DHA is currently used worldwide to treat malaria by killing malaria-causing parasites. In...
19.
Guo Z, Li H, Han M, Xu T, Wu X, Zhuang Y
Immunol Lett
. 2010 Oct;
135(1-2):34-42.
PMID: 20932862
The Id3 gene has been shown to play important roles in the development and function of broad tissue types including B and T cells. Id3 deficient mice develop autoimmune disease...