Zdenek Krejcik
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Explore the profile of Zdenek Krejcik including associated specialties, affiliations and a list of published articles.
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45
Citations
311
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Recent Articles
1.
Krejcik Z, Kundrat D, Klema J, Hrustincova A, Trsova I, Belickova M, et al.
Biomark Res
. 2025 Jan;
13(1):13.
PMID: 39849644
Background: Myelodysplastic neoplasms (MDS) are heterogeneous hematopoietic disorders characterized by ineffective hematopoiesis and genome instability. Mobilization of transposable elements (TEs) is an important source of genome instability leading to oncogenesis,...
2.
Saveleva L, Cervena T, Mengoni C, Sima M, Krejcik Z, Vrbova K, et al.
Alzheimers Dement
. 2024 Nov;
20(12):8825-8843.
PMID: 39579047
Introduction: Studies have correlated living close to major roads with Alzheimer's disease (AD) risk. However, the mechanisms responsible for this link remain unclear. Methods: We exposed olfactory mucosa (OM) cells...
3.
Mussalo L, Lampinen R, Avesani S, Zavodna T, Krejcik Z, Kalapudas J, et al.
Redox Biol
. 2024 Jul;
75:103272.
PMID: 39047637
Constituents of air pollution, the ultrafine particles (UFP) with a diameter of ≤0.1 μm, are considerably related to traffic emissions. Several studies link air pollution to Alzheimer's disease (AD), yet...
4.
Simova Z, Sima M, Pelclova D, Klusackova P, Zdimal V, Schwarz J, et al.
Nanomedicine (Lond)
. 2024 Jul;
19(17):1511-1523.
PMID: 38953869
Today, there is a lack of research studies concerning human acute exposure to nanoparticles (NPs). Our investigation aimed to simulate real-world acute inhalation exposure to NPs released during work with...
5.
Kaisrlikova M, Kundrat D, Koralkova P, Trsova I, Lenertova Z, Votavova H, et al.
Int J Cancer
. 2024 Jan;
154(9):1652-1668.
PMID: 38180088
Patients with myelodysplastic neoplasms (MDS) are classified according to the risk of acute myeloid leukemia transformation. Some lower-risk MDS patients (LR-MDS) progress rapidly despite expected good prognosis. Using diagnostic samples,...
6.
Shahbaz M, Kuivanen S, Lampinen R, Mussalo L, Hron T, Zavodna T, et al.
J Neuroinflammation
. 2023 Dec;
20(1):299.
PMID: 38098019
Background: The neurological effects of the coronavirus disease of 2019 (COVID-19) raise concerns about potential long-term consequences, such as an increased risk of Alzheimer's disease (AD). Neuroinflammation and other AD-associated...
7.
Saveleva L, Sima M, Klema J, Krejcik Z, Vartiainen P, Sitnikova V, et al.
Environ Toxicol Pharmacol
. 2023 Nov;
104:104316.
PMID: 37981204
This study evaluated how exposure to the ubiquitous air pollution component, ultrafine particles (UFPs), alters the olfactory bulb (OB) transcriptome. The study utilised a whole-body inhalation chamber to simulate real-life...
8.
Mussalo L, Avesani S, Shahbaz M, Zavodna T, Saveleva L, Jarvinen A, et al.
Sci Total Environ
. 2023 Sep;
905:167038.
PMID: 37709087
Ultrafine particles (UFP) with a diameter of ≤0.1 μm, are contributors to ambient air pollution and derived mainly from traffic emissions, yet their health effects remain poorly characterized. The olfactory...
9.
Trsova I, Hrustincova A, Krejcik Z, Kundrat D, Holoubek A, Staflova K, et al.
Mol Oncol
. 2023 Jul;
17(12):2565-2583.
PMID: 37408496
Mutations in the splicing factor 3b subunit 1 (SF3B1) gene are frequent in myelodysplastic neoplasms (MDS). Because the splicing process is involved in the production of circular RNAs (circRNAs), we...
10.
Kaisrlikova M, Vesela J, Kundrat D, Votavova H, Dostalova Merkerova M, Krejcik Z, et al.
Leukemia
. 2022 May;
36(7):1898-1906.
PMID: 35505182
Patients with lower-risk myelodysplastic syndromes (LR-MDS) have a generally favorable prognosis; however, a small proportion of cases progress rapidly. This study aimed to define molecular biomarkers predictive of LR-MDS progression...