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Zbigniew Darzynkiewicz

Explore the profile of Zbigniew Darzynkiewicz including associated specialties, affiliations and a list of published articles. Areas
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Articles 248
Citations 5281
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Recent Articles
1.
Gupta A, Carnazza M, Jones M, Darzynkiewicz Z, Halicka D, OConnell T, et al.
Cancers (Basel) . 2024 Nov; 16(21). PMID: 39518160
In the original publication [...].
2.
Gupta A, Carnazza M, Jones M, Darzynkiewicz Z, Halicka D, OConnell T, et al.
Cancers (Basel) . 2023 May; 15(8). PMID: 37190127
Thyroid cancer (TC) is the most common endocrine malignancy, with an approximately three-fold higher incidence in women. TCGA data indicate that androgen receptor (AR) RNA is significantly downregulated in PTC....
3.
Hao S, Salzo J, Zhao H, Hao M, Darzynkiewicz Z, Ferreri N
Hypertension . 2020 Nov; 76(6):1744-1752. PMID: 33131307
We showed that intrarenal suppression of TNF (tumor necrosis factor) production under low salt (LS) conditions increases renal cortical AGT (angiotensinogen) mRNA and protein expression. Intrarenal injection of murine recombinant...
4.
Ravera S, Ghiotto F, Tenca C, Gugiatti E, Santamaria S, Ledda B, et al.
Sci Rep . 2020 Oct; 10(1):16519. PMID: 33020573
B-cell chronic lymphocytic leukemia (CLL) results from accumulation of leukemic cells that are subject to iterative re-activation cycles and clonal expansion in lymphoid tissues. The effects of the well-tolerated alkaloid...
5.
Darzynkiewicz Z
Cytometry A . 2020 Jun; 97(6):557-562. PMID: 32511890
Briefly depicted are the publications in CYTOMETRY that received the highest frequency of citations. Among them are seminal papers describing application of metachromatic fluorochrome acridine orange to differentially stain DNA...
6.
Stobezki R, Titus S, Halicka D, Darzynkiewicz Z, Oktay K
Reprod Sci . 2020 Jan; 27(3):940-953. PMID: 31916095
Recent data suggest that paternal age can have major impact on reproductive outcomes, and with increased age, there is increased likelihood of chromosomal abnormalities in the sperm. Here, we studied...
7.
Darzynkiewicz Z, Halicka D, Zhao H, Li J
Curr Protoc Cytom . 2019 Nov; 91(1):e65. PMID: 31763788
The susceptibility of DNA in situ to denaturation is modulated by its interactions with histone and nonhistone proteins, as well as with other chromatin components related to the maintenance of...
8.
Lee M, Zhang S, Wang X, Chao H, Zhao H, Darzynkiewicz Z, et al.
DNA Repair (Amst) . 2019 Jul; 81:102656. PMID: 31326365
DNA polymerase δ (Pol δ) plays a central role in lagging strand DNA synthesis in eukaryotic cells, as well as an important role in DNA repair processes. Human Pol δ4...
9.
Zhao H, Huang X, Halicka H, Darzynkiewicz Z
Curr Protoc Cytom . 2019 Jun; 89(1):e55. PMID: 31237414
This unit describes immunocytochemical detection of histone H2AX phosphorylated on Ser-139 (γH2AX) to reveal DNA damage, particularly when the damage involves the presence of DNA double-strand breaks (DSBs). These breaks...
10.
Li W, Stevens C, Pandya A, Darzynkiewicz Z, Bhattarai P, Tong W, et al.
ACS Infect Dis . 2019 Mar; 5(6):1001-1012. PMID: 30882198
MmpL3, an essential transporter involved in the export of mycolic acids, is the proposed target of a number of antimycobacterial inhibitors under development. Whether MmpL3 serves as the direct target...