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Zack Z Wang

Explore the profile of Zack Z Wang including associated specialties, affiliations and a list of published articles. Areas
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Articles 39
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Recent Articles
1.
Zhang S, Qu K, Lyu S, Hoyle D, Smith C, Cheng L, et al.
J Cell Physiol . 2022 Nov; 238(1):179-194. PMID: 36436185
Hemogenic endothelial (HE) cells are specialized endothelial cells to give rise to hematopoietic stem/progenitor cells during hematopoietic development. The underlying mechanisms that regulate endothelial-to-hematopoietic transition (EHT) of human HE cells...
2.
Shen J, Xu Y, Zhang S, Lyu S, Huo Y, Zhu Y, et al.
Sci Adv . 2021 Sep; 7(36):eabi9787. PMID: 34516916
Hematopoietic differentiation of human pluripotent stem cells (hPSCs) requires orchestration of dynamic cell and gene regulatory networks but often generates blood cells that lack natural function. Here, we performed extensive...
3.
Kruse R, Huang Y, Lee A, Zhu X, Shrestha R, Laeyendecker O, et al.
J Clin Microbiol . 2021 Sep; 59(12):e0118621. PMID: 34469185
Serologic point-of-care tests to detect antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are an important tool in the COVID-19 pandemic. The majority of current point-of-care antibody tests developed...
4.
Kruse R, Huang Y, Shum T, Bai L, Ding H, Wang Z, et al.
Gastrointest Endosc . 2021 Jul; 94(6):1119-1130.e4. PMID: 34197834
Background And Aims: Gene therapy could provide curative therapies to many inherited monogenic liver diseases. Clinical trials have largely focused on adeno-associated viruses (AAVs) for liver gene delivery. These vectors,...
5.
Kruse R, Huang Y, Lee A, Zhu X, Shrestha R, Laeyendecker O, et al.
medRxiv . 2021 May; PMID: 33972952
Serologic, point-of-care tests to detect antibodies against SARS-CoV-2 are an important tool in the COVID-19 pandemic. The majority of current point-of-care antibody tests developed for SARS-CoV-2 rely on lateral flow...
6.
Huang Y, Kruse R, Ding H, Itani M, Morrison J, Wang Z, et al.
PLoS One . 2021 Apr; 16(4):e0249931. PMID: 33909609
The biliary system is routinely accessed for clinical purposes via endoscopic retrograde cholangiopancreatography (ERCP). We previously pioneered ERCP-mediated hydrodynamic injection in large animal models as an innovative gene delivery approach...
7.
Kammers K, Taub M, Mathias R, Yanek L, Kanchan K, Venkatraman V, et al.
J Thromb Haemost . 2021 Apr; 19(7):1783-1799. PMID: 33829634
Background: There is interest in deriving megakaryocytes (MKs) from pluripotent stem cells (iPSC) for biological studies. We previously found that genomic structural integrity and genotype concordance is maintained in iPSC-derived...
8.
Kruse R, Huang Y, Smetana H, Gehrie E, Amukele T, Tobian A, et al.
Biochem Biophys Res Commun . 2021 Mar; 553:165-171. PMID: 33773139
The COVID-19 pandemic has caused significant morbidity and mortality. There is an urgent need for serological tests to detect antibodies against SARS-CoV-2, which could be used to assess past infection,...
9.
Shen J, Zhu Y, Zhang S, Lyu S, Lyu C, Feng Z, et al.
Cell Prolif . 2021 Mar; 54(4):e13012. PMID: 33656760
Objectives: Vitronectin (VTN) has been widely used for the maintenance and expansion of human pluripotent stem cells (hPSCs) as feeder-free conditions. However, the effect of VTN on hPSC differentiation remains...
10.
Kammers K, Taub M, Rodriguez B, Yanek L, Ruczinski I, Martin J, et al.
Blood . 2020 Oct; 137(7):959-968. PMID: 33094331
Genome-wide association studies have identified common variants associated with platelet-related phenotypes, but because these variants are largely intronic or intergenic, their link to platelet biology is unclear. In 290 normal...