Zachary I Grunewald
Overview
Explore the profile of Zachary I Grunewald including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
275
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0
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Recent Articles
1.
Hechenbleikner E, Majumdar M, Gillingham T, Jannuzzo C, Grunewald Z, Sanford J, et al.
Surg Endosc
. 2022 Jun;
37(2):1449-1457.
PMID: 35764842
Background: Enhanced recovery protocols (ERPs) after metabolic and bariatric surgery (MBS) may help decrease length of stay (LOS) and postoperative nausea/vomiting but implementation is often fraught with challenges. The primary...
2.
Ramirez-Perez F, Woodford M, Morales-Quinones M, Grunewald Z, Cabral-Amador F, Yoshida T, et al.
Am J Physiol Heart Circ Physiol
. 2021 Jul;
321(2):H435-H445.
PMID: 34242094
Arterial stiffening, a characteristic feature of obesity and type 2 diabetes, contributes to the development and progression of cardiovascular diseases (CVD). Currently, no effective prophylaxis or therapeutics is available to...
3.
Grunewald Z, Ramirez-Perez F, Woodford M, Morales-Quinones M, Mejia S, Manrique-Acevedo C, et al.
Hypertension
. 2020 Aug;
76(4):1319-1329.
PMID: 32829657
Insulin resistance in the vasculature is a characteristic feature of obesity and contributes to the pathogenesis of vascular dysfunction and disease. However, the molecular mechanisms underlying obesity-associated vascular insulin resistance...
4.
Sales A, Azevedo L, Silva T, Rodrigues A, Oliveira P, Jordao C, et al.
Circ Heart Fail
. 2020 Jul;
13(8):e007121.
PMID: 32673501
No abstract available.
5.
Limberg J, Smith J, Soares R, Harper J, Houghton K, Jacob D, et al.
Am J Physiol Heart Circ Physiol
. 2020 Jun;
319(1):H162-H170.
PMID: 32502373
Vasodilatory effects of insulin support the delivery of insulin and glucose to skeletal muscle. Concurrently, insulin exerts central effects that increase sympathetic nervous system activity (SNA), which is required for...
6.
Grunewald Z, Jurrissen T, Woodford M, Ramirez-Perez F, Park L, Pettit-Mee R, et al.
Hypertension
. 2019 Oct;
74(6):1409-1419.
PMID: 31630572
Endothelin-1 (ET-1) is a powerful vasoconstrictor peptide considered to be causally implicated in hypertension and the development of cardiovascular disease. Increased ET-1 is commonly associated with reduced NO bioavailability and...
7.
Olver T, Grunewald Z, Ghiarone T, Restaino R, Sales A, Park L, et al.
Am J Physiol Heart Circ Physiol
. 2019 Oct;
317(5):H1166-H1172.
PMID: 31603345
Insulin modulates vasomotor tone through vasodilator and vasoconstrictor signaling pathways. The purpose of the present work was to determine whether insulin-stimulated vasoconstriction is a pathophysiological phenomenon that can result from...
8.
Lee S, Kirkland R, Grunewald Z, Sun Q, Wicker L, de La Serre C
Nutrients
. 2019 Aug;
11(9).
PMID: 31443365
Development of obesity-associated comorbidities is related to chronic inflammation, which has been linked to gut microbiota dysbiosis. Thus, modulating gut microbiota composition could have positive effects for metabolic disorders, supporting...
9.
Jurrissen T, Grunewald Z, Woodford M, Winn N, Ball J, Smith T, et al.
Am J Physiol Endocrinol Metab
. 2019 Jul;
317(3):E548-E558.
PMID: 31310581
Endothelin-1 (ET-1) is a potent vasoconstrictor and proinflammatory peptide that is upregulated in obesity. Herein, we tested the hypothesis that ET-1 signaling promotes visceral adipose tissue (AT) inflammation and disrupts...
10.
Winn N, Jurrissen T, Grunewald Z, Cunningham R, Woodford M, Kanaley J, et al.
Am J Physiol Endocrinol Metab
. 2018 Dec;
316(2):E156-E167.
PMID: 30512987
The role of estrogen receptor-α (ERα) signaling in immunometabolic function is established in females. However, its necessity in males, while appreciated, requires further study. Accordingly, we first determined whether lower...