Zachary Glass
Overview
Explore the profile of Zachary Glass including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
663
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0
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Recent Articles
1.
Li Y, Glass Z, Xu Q
Methods Mol Biol
. 2022 Jan;
2394:555-573.
PMID: 35094346
Protein-based therapeutics are a class of drugs considered to be one of most safe and straightforward approaches for manipulating cell function and treating diseases. However, in contrast to traditional small-molecule...
2.
Chen J, Qiu M, Ye Z, Nyalile T, Li Y, Glass Z, et al.
Sci Adv
. 2021 May;
7(19).
PMID: 33952519
In situ vaccination is a promising strategy for cancer immunotherapy owing to its convenience and the ability to induce numerous tumor antigens. However, the advancement of in situ vaccination techniques...
3.
Qiu M, Glass Z, Chen J, Haas M, Jin X, Zhao X, et al.
Proc Natl Acad Sci U S A
. 2021 Mar;
118(10).
PMID: 33649229
Loss-of-function mutations in Angiopoietin-like 3 () are associated with lowered blood lipid levels, making an attractive therapeutic target for the treatment of human lipoprotein metabolism disorders. In this study, we...
4.
Liu F, Yang L, Li Y, Junier A, Ma F, Chen J, et al.
ACS Biomater Sci Eng
. 2021 Jan;
6(2):1064-1073.
PMID: 33464849
Invasive fungal infections are well-known causes of morbidity and mortality in immunocompromised patients. Amphotericin B (AmB) is a polyene fungicidal agent with excellent properties of the broad antifungal spectrum, high...
5.
Chen J, Qiu M, Ma F, Yang L, Glass Z, Xu Q
J Control Release
. 2020 Nov;
330:1244-1249.
PMID: 33234362
Proteolysis-targeting chimaera (PROTAC) technology is an emerging approach for achieving targeted degradation of a protein of interest (POI) intracellularly. However, the cell permeability of PROTACs is limited by their high...
6.
Ma F, Yang L, Sun Z, Chen J, Rui X, Glass Z, et al.
Sci Adv
. 2020 Aug;
6(30):eabb4429.
PMID: 32832671
Safe and efficient delivery of blood-brain barrier (BBB)-impermeable cargos into the brain through intravenous injection remains a challenge. Here, we developed a previously unknown class of neurotransmitter-derived lipidoids (NT-lipidoids) as...
7.
Zhao X, Glass Z, Chen J, Yang L, Kaplan D, Xu Q
Adv Healthc Mater
. 2020 Aug;
10(4):e2000938.
PMID: 32815325
Mesenchymal stem cells (MSCs) are widely used in regenerative medicine and tissue engineering and delivering biological molecules into MSCs has been used to control stem cell behavior. However, the efficient...
8.
Zhao X, Chen J, Qiu M, Li Y, Glass Z, Xu Q
Angew Chem Int Ed Engl
. 2020 Jul;
59(45):20083-20089.
PMID: 32662132
Engineering T lymphocytes is an emerging approach in a variety of biomedical applications. However, delivering large biologics to primary T lymphocytes directly in vivo is technically challenging due to the...
9.
Li Y, Jarvis R, Zhu K, Glass Z, Ogurlu R, Gao P, et al.
Angew Chem Int Ed Engl
. 2020 May;
59(35):14957-14964.
PMID: 32438474
Developing safe and efficient delivery systems for therapeutic biomacromolecules is a long-standing challenge. Herein, we report a newly developed combinatorial library of cholesteryl-based disulfide bond-containing biodegradable cationic lipidoid nanoparticles. We...
10.
Li Y, Glass Z, Huang M, Chen Z, Xu Q
Biomaterials
. 2020 Jan;
234:119711.
PMID: 31945616
The recently developed CRISPR/Cas9 technology has revolutionized the genome engineering field. Since 2016, increasing number of studies regarding CRISPR therapeutics have entered clinical trials, most of which are focusing on...