Zachariah P Tritz
Overview
Explore the profile of Zachariah P Tritz including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
11
Citations
173
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Fain C, Zheng J, Jin F, Ayasoufi K, Wu Y, Lilley M, et al.
Brain
. 2023 Sep;
147(2):566-589.
PMID: 37776513
Cerebral malaria is the deadliest complication that can arise from Plasmodium infection. CD8 T-cell engagement of brain vasculature is a putative mechanism of neuropathology in cerebral malaria. To define contributions...
2.
Ayasoufi K, Wolf D, Namen S, Jin F, Tritz Z, Pfaller C, et al.
Brain Behav Immun
. 2023 May;
112:51-76.
PMID: 37236326
The contribution of circulating verses tissue resident memory T cells (TRMs) to clinical neuropathology is an enduring question due to a lack of mechanistic insights. The prevailing view is TRMs...
3.
Lorrey S, Waibl Polania J, Wachsmuth L, Hoyt-Miggelbrink A, Tritz Z, Edwards R, et al.
Neurooncol Adv
. 2023 May;
5(1):vdad035.
PMID: 37207119
Background: The nervous and immune systems interact in a reciprocal manner, both under physiologic and pathologic conditions. Literature spanning various CNS pathologies including brain tumors, stroke, traumatic brain injury and...
4.
Tritz Z, Ayasoufi K, Wolf D, Owens C, Malo C, Himes B, et al.
Cancer Immunol Res
. 2023 Mar;
11(6):763-776.
PMID: 36921098
Glioblastoma (GBM) is the most common malignant brain tumor in adults, responsible for approximately 225,000 deaths per year. Despite preclinical successes, most interventions have failed to extend patient survival by...
5.
Zhang X, Pearsall V, Carver C, Atkinson E, Clarkson B, Grund E, et al.
Nat Commun
. 2022 Sep;
13(1):5671.
PMID: 36167854
Cellular senescence is a plausible mediator of inflammation-related tissue dysfunction. In the aged brain, senescent cell identities and the mechanisms by which they exert adverse influence are unclear. Here we...
6.
Himes B, Fain C, Tritz Z, Nesvick C, Jin-Lee H, Geiger P, et al.
J Neurosurg
. 2022 Sep;
138(5):1291-1301.
PMID: 36115048
Objective: The profound immunosuppression found in glioblastoma (GBM) patients is a critical barrier to effective immunotherapy. Multiple mechanisms of tumor-mediated immune suppression exist, and the induction of immunosuppressive monocytes such...
7.
Goddery E, Fain C, Lipovsky C, Ayasoufi K, Yokanovich L, Malo C, et al.
Front Immunol
. 2021 Sep;
12:726421.
PMID: 34526998
CD8 T cell infiltration of the central nervous system (CNS) is necessary for host protection but contributes to neuropathology. Antigen presenting cells (APCs) situated at CNS borders are thought to...
8.
Tritz Z, Ayasoufi K, Johnson A
Neurooncol Adv
. 2021 Jun;
3(1):vdab066.
PMID: 34151268
The GL261 cell line, syngeneic on the C57BL/6 background, has, since its establishment half a century ago in 1970, become the most commonly used immunocompetent murine model of glioblastoma. As...
9.
Ayasoufi K, Pfaller C, Evgin L, Khadka R, Tritz Z, Goddery E, et al.
Brain
. 2020 Nov;
143(12):3629-3652.
PMID: 33253355
Immunosuppression of unknown aetiology is a hallmark feature of glioblastoma and is characterized by decreased CD4 T-cell counts and downregulation of major histocompatibility complex class II expression on peripheral blood...
10.
Tritz Z, Orozco R, Malo C, Ayasoufi K, Fain C, Khadka R, et al.
J Immunol
. 2020 Aug;
205(5):1228-1238.
PMID: 32737149
Theiler's murine encephalomyelitis virus (TMEV) infection of the CNS is cleared in C57BL/6 mice by a CD8 T cell response restricted by the MHC class I molecule H-2D The identity...