Michael J Hansen
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Explore the profile of Michael J Hansen including associated specialties, affiliations and a list of published articles.
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61
Citations
1088
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Recent Articles
1.
Liang Y, Ozdogan E, Hansen M, Tang H, Saadiq I, Jordan K, et al.
Front Immunol
. 2024 Aug;
15:1448092.
PMID: 39104523
Introduction: The immunomodulatory properties of mesenchymal stromal cells (MSC) have been well-characterized in and models. We have previously shown that liver MSC (L-MSC) are superior inhibitors of T-cell activation/proliferation, NK...
2.
Zhou X, Li M, Ai M, Li Y, Zhu X, Hansen M, et al.
Eur J Immunol
. 2024 Jul;
54(10):e2451080.
PMID: 39072720
Although the functions of tyrosine phosphatases in T-cell biology have been extensively studied, our knowledge on the contribution of serine/threonine phosphatases in T cells remains poor. Protein phosphatase 2A (PP2A)...
3.
Zhou X, Li M, Ai M, Li Y, Zhu X, Hansen M, et al.
bioRxiv
. 2024 Feb;
PMID: 38370780
While the functions of tyrosine phosphatases in T cell biology have been extensively studied, our knowledge on the contribution of serine/threonine phosphatases in T cells remains poor. Protein phosphatase 2A...
4.
Fain C, Zheng J, Jin F, Ayasoufi K, Wu Y, Lilley M, et al.
Brain
. 2023 Sep;
147(2):566-589.
PMID: 37776513
Cerebral malaria is the deadliest complication that can arise from Plasmodium infection. CD8 T-cell engagement of brain vasculature is a putative mechanism of neuropathology in cerebral malaria. To define contributions...
5.
Sakemura R, Hefazi M, Cox M, Siegler E, Sinha S, Hansen M, et al.
Cancer Immunol Res
. 2023 Jun;
11(9):1222-1236.
PMID: 37378662
The receptor tyrosine kinase AXL is a member of the TYRO3, AXL, and proto-oncogene tyrosine-protein kinase MER family and plays pleiotropic roles in cancer progression. AXL is expressed in immunosuppressive...
6.
Ayasoufi K, Wolf D, Namen S, Jin F, Tritz Z, Pfaller C, et al.
Brain Behav Immun
. 2023 May;
112:51-76.
PMID: 37236326
The contribution of circulating verses tissue resident memory T cells (TRMs) to clinical neuropathology is an enduring question due to a lack of mechanistic insights. The prevailing view is TRMs...
7.
Tritz Z, Ayasoufi K, Wolf D, Owens C, Malo C, Himes B, et al.
Cancer Immunol Res
. 2023 Mar;
11(6):763-776.
PMID: 36921098
Glioblastoma (GBM) is the most common malignant brain tumor in adults, responsible for approximately 225,000 deaths per year. Despite preclinical successes, most interventions have failed to extend patient survival by...
8.
Yigitbilek F, Ozdogan E, Abrol N, Park W, Hansen M, Dasari S, et al.
Front Immunol
. 2022 Oct;
13:952262.
PMID: 36211345
Liver-resident mesenchymal stem cells (L-MSCs) are superior inhibitors of alloreactive T cell responses compared to their counterparts from bone marrow (BM-MSCs) or adipose tissue (A-MSCs), suggesting a role in liver's...
9.
Mudrick H, Massey S, McGlinch E, Parrett B, Hemsath J, Barry M, et al.
Sci Adv
. 2022 Aug;
8(34):eabm8563.
PMID: 36001674
Most gene-based severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines are nonreplicating vectors. They deliver the gene or messenger RNA to the cell to express the spike protein but do...
10.
Sakemura R, Hefazi M, Siegler E, Cox M, Larson D, Hansen M, et al.
Blood
. 2022 Jan;
139(26):3708-3721.
PMID: 35090171
Pivotal clinical trials of B-cell maturation antigen-targeted chimeric antigen receptor T (CART)-cell therapy in patients with relapsed/refractory multiple myeloma (MM) resulted in remarkable initial responses, which led to a recent...