Zach N Adelman
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Explore the profile of Zach N Adelman including associated specialties, affiliations and a list of published articles.
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84
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1951
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Recent Articles
1.
Dingle A, Adelman Z
PLoS One
. 2024 Dec;
19(12):e0309095.
PMID: 39625906
Flaviviruses are a diverse group of RNA viruses known for their significant impact on human health worldwide. We generated a series of reporters that included cleavage sequences from the dengue...
2.
Chennuri P, Zapletal J, Monfardini R, Ndeffo-Mbah M, Adelman Z, Myles K
PLoS Genet
. 2024 Nov;
20(11):e1011450.
PMID: 39509462
Here, we demonstrate that single strand annealing (SSA) can be co-opted for the precise autocatalytic excision of a drive element. We have termed this technology Repeat Mediated Excision of a...
3.
Petersen V, Santana M, Karina-Costa M, Nachbar J, Martin-Martin I, Adelman Z, et al.
Insects
. 2024 Aug;
15(8).
PMID: 39194805
More than 3550 species of mosquitoes are known worldwide, and only a fraction is involved in the transmission of arboviruses. Mosquitoes in sylvatic and semi-sylvatic habitats may rapidly adapt to...
4.
Chae K, Contreras B, Romanowski J, Dawson C, Myles K, Adelman Z
Commun Biol
. 2024 May;
7(1):660.
PMID: 38811748
While gene drive strategies have been proposed to aid in the control of mosquito-borne diseases, additional genome engineering technologies may be required to establish a defined end-of-product-life timeline. We previously...
5.
Shetty V, Adelman Z, Slotman M
BMC Genomics
. 2024 Feb;
25(1):170.
PMID: 38347446
Background: This study explores the impact of disrupting the circadian clock through a Cycle gene knockout (KO) on the transcriptome of Aedes aegypti mosquitoes. The investigation aims to uncover the...
6.
Chennuri P, Zapletal J, Monfardini R, Ndeffo-Mbah M, Adelman Z, Myles K
bioRxiv
. 2023 Dec;
PMID: 38045402
We demonstrate here that single strand annealing (SSA) repair can be co-opted for the precise autocatalytic excision of a drive element. Although SSA is not the predominant form of DNA...
7.
Anderson M, Leftwich P, Wilson R, Paladino L, Basu S, Rooney S, et al.
Sci Rep
. 2023 Nov;
13(1):20352.
PMID: 37990055
Molecular tools for modulating transgene expression in Aedes aegypti are few. Here we demonstrate that adjustments to the AePUb promoter length can alter expression levels of two reporter proteins in...
8.
Martin-Martin I, Kojin B, Aryan A, Williams A, Molina-Cruz A, Valenzuela-Leon P, et al.
mBio
. 2023 Nov;
14(6):e0228923.
PMID: 37909749
During blood feeding, mosquitoes inject saliva into the host skin, preventing hemostasis and inflammatory responses. D7 proteins are among the most abundant components of the saliva of blood-feeding arthropods. ,...
9.
Liu X, Goldsmith C, Kang K, Vedlitz A, Adelman Z, Buchman L, et al.
Risk Anal
. 2023 Oct;
44(6):1381-1395.
PMID: 37882685
With limited understanding of most new biotechnologies, how do citizens form their opinion and what factors influence their attitudes about these innovations? In this study, we use gene drive biotechnology...
10.
Contreras B, Adelman Z, Chae K
Front Trop Dis
. 2023 Oct;
4.
PMID: 37860147
Efforts to eradicate mosquito-borne diseases have increased the demand for genetic control strategies, many of which involve the release of genetically modified (GM) mosquito males into natural populations. The first...