Z Siprashvili
Overview
Explore the profile of Z Siprashvili including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
734
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0
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Recent Articles
1.
Gorell E, Nguyen N, Siprashvili Z, Marinkovich M, Lane A
Br J Dermatol
. 2015 Feb;
173(3):821-3.
PMID: 25703736
No abstract available.
2.
McCorkell K, Mancini R, Siprashvili Z, Barnoski B, Iliopoulos D, Siracusa L, et al.
Cytogenet Genome Res
. 2007 Nov;
118(2-4):196-203.
PMID: 18000371
FHIT, at a constitutively active chromosome fragile site, is often a target of chromosomal aberrations and deletion in a large fraction of human tumors. Inactivation of murine Fhit allelessignificantly increases...
3.
Werner N, Siprashvili Z, Fong L, Marquitan G, Schroder J, Bardenheuer W, et al.
Cancer Res
. 2000 Jun;
60(11):2780-5.
PMID: 10850413
Hemizygous deletions of the fragile histidine triad (FHIT) gene at human chromosome band 3p14.2 and down-regulation of its gene product are found in the majority of renal cell carcinomas (RCCs)....
4.
Fong L, Fidanza V, Zanesi N, Lock L, Siracusa L, Mancini R, et al.
Proc Natl Acad Sci U S A
. 2000 Apr;
97(9):4742-7.
PMID: 10758156
To investigate the role of the Fhit gene in carcinogen induction of neoplasia, we have inactivated one Fhit allele in mouse embryonic stem cells and produced (129/SvJ x C57BL/6J) F(1)...
5.
Huebner K, Druck T, Siprashvili Z, Croce C, Kovatich A, McCue P
Recent Results Cancer Res
. 1999 Feb;
154:200-15.
PMID: 10027001
The FHIT gene, which encodes a 1-kb message and a 16.8-kDa protein that hydrolyses diadenosine triphosphate (ApppA) to ADP and AMP in vitro, covers a megabase genomic region at chromosome...
6.
Hadaczek P, Siprashvili Z, Markiewski M, Domagala W, Druck T, McCue P, et al.
Cancer Res
. 1998 Jul;
58(14):2946-51.
PMID: 9679951
The FHIT gene at human chromosome region 3p14.2 straddles the common fragile site, FRA3B, and numerous homozygous deletions in cancer cell lines and primary tumors. Also, the 3p14.2 chromosome breakpoint...
7.
Pekarsky Y, Campiglio M, Siprashvili Z, Druck T, Sedkov Y, Tillib S, et al.
Proc Natl Acad Sci U S A
. 1998 Jul;
95(15):8744-9.
PMID: 9671749
The tumor suppressor gene FHIT encompasses the common human chromosomal fragile site at 3p14.2 and numerous cancer cell biallelic deletions. To study Fhit function we cloned and characterized FHIT genes...
8.
Pace H, Garrison P, Robinson A, Barnes L, Draganescu A, Rosler A, et al.
Proc Natl Acad Sci U S A
. 1998 May;
95(10):5484-9.
PMID: 9576908
Alterations in the FHIT gene at 3p14.2 occur as early and frequent events in the development of several common human cancers. The ability of human Fhit-negative cells to form tumors...
9.
Siprashvili Z, Sozzi G, Barnes L, McCue P, Robinson A, Eryomin V, et al.
Proc Natl Acad Sci U S A
. 1998 Feb;
94(25):13771-6.
PMID: 9391102
The candidate tumor suppressor gene, FHIT, encompasses the common human chromosomal fragile site at 3p14.2, the hereditary renal cancer translocation breakpoint, and cancer cell homozygous deletions. Fhit hydrolyzes dinucleotide 5',5"'-P1,P3-triphosphate...
10.
Huebner K, Hadaczek P, Siprashvili Z, Druck T, Croce C
Biochim Biophys Acta
. 1997 Jun;
1332(3):M65-70.
PMID: 9196019
No abstract available.