Z SELINGER
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Explore the profile of Z SELINGER including associated specialties, affiliations and a list of published articles.
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117
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2116
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Recent Articles
1.
Chen F, SELINGER Z, Marks P, Belinsky G, TASHJIAN Jr A
Biochem Biophys Res Commun
. 2001 Jul;
285(3):742-50.
PMID: 11453656
Despite attempts in several laboratories, it has been difficult to prepare antiserum to the thyrotropin-releasing hormone receptor (TRHR). We have prepared a polyclonal anti-rat TRHR antiserum by immunization of rabbits...
2.
Frechter S, Gillo B, SELINGER Z, Gill D, Minke B
J Neurosci
. 2001 Apr;
21(8):2622-9.
PMID: 11306615
Drosophila phototransduction is an important model system for studies of inositol lipid signaling. Light excitation in Drosophila photoreceptors depends on phospholipase C, because null mutants of this enzyme do not...
3.
Kosloff M, SELINGER Z
Trends Biochem Sci
. 2001 Mar;
26(3):161-6.
PMID: 11246021
The idea that both the substrate and the enzyme contribute to catalysis (substrate assisted catalysis; SAC) is applicable to guanine nucleotide-binding proteins (G proteins). Naturally occurring SAC uses GTP as...
4.
Raghu P, Colley N, Webel R, James T, Hasan G, Danin M, et al.
Mol Cell Neurosci
. 2000 Jun;
15(5):429-45.
PMID: 10833300
The Drosophila light-sensitive channels TRP and TRPL are prototypical members of an ion channel family responsible for a variety of receptor-mediated Ca(2+) influx phenomena, including store-operated calcium influx. While phospholipase...
5.
Cook B, Cohen Ben-Ami H, Goldstein R, Paroush Z, SELINGER Z, Minke B
Nat Cell Biol
. 2000 May;
2(5):296-301.
PMID: 10806481
In Drosophila photoreceptors, phospholipase C (PLC) and other signalling components form multiprotein structures through the PDZ scaffold protein INAD. Association between PLC and INAD is important for termination of responses...
6.
Chyb S, Hevers W, Forte M, Wolfgang W, SELINGER Z, Hardie R
J Neurosci
. 1999 Oct;
19(20):8799-807.
PMID: 10516299
Phototransduction in Drosophila is mediated by a G-protein-coupled phospholipase C transduction cascade in which each absorbed photon generates a discrete electrical event, the quantum bump. In whole-cell voltage-clamp recordings, cAMP,...
7.
Ahmadian M, Zor T, Vogt D, Kabsch W, SELINGER Z, Wittinghofer A, et al.
Proc Natl Acad Sci U S A
. 1999 Jun;
96(12):7065-70.
PMID: 10359839
Interest in the guanosine triphosphatase (GTPase) reaction of Ras as a molecular drug target stems from the observation that, in a large number of human tumors, Ras is characteristically mutated...
8.
Zor T, Andorn R, SOFER I, Chorev M, SELINGER Z
FEBS Lett
. 1998 Sep;
433(3):326-30.
PMID: 9744820
Hydrolysis of GTP, bound to members of the G-protein superfamily, terminates their downstream signaling activity. A conserved glutamine serves a critical role in this pivotal guanosine triphosphatase (GTPase) reaction. However,...
9.
Zor T, Elgavish S, Shaanan B, SELINGER Z
Eur J Biochem
. 1997 Nov;
249(1):330-6.
PMID: 9363787
Signaling by guanine-nucleotide-binding proteins (G-proteins) occurs when they are charged with GTP, while hydrolysis of the bound nucleotide turns the signaling off. Despite a wealth of biochemical and structural information,...
10.
ARNON A, Cook B, Gillo B, Montell C, SELINGER Z, Minke B
Proc Natl Acad Sci U S A
. 1997 May;
94(11):5894-9.
PMID: 9159171
Phototransduction in Drosophila occurs through inositol lipid signaling that results in Ca2+ mobilization. In this system, we investigate the hitherto unknown physiological roles of calmodulin (CaM) in light adaptation and...