Yvonne Dempsie
Overview
Explore the profile of Yvonne Dempsie including associated specialties, affiliations and a list of published articles.
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25
Citations
932
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Recent Articles
1.
Wali S, Hwej A, Welsh D, Wilson K, Kennedy S, Dempsie Y
Int J Mol Sci
. 2025 Feb;
26(3).
PMID: 39941047
Pulmonary hypertension (PH) is a complex condition characterized by pulmonary artery constriction and vascular remodeling. Connexin 43 (Cx43), involved in cellular communication, may play a role in PH development. Cx43...
2.
Htet M, Nally J, Martin P, Dempsie Y
Int J Mol Sci
. 2022 Jan;
23(1).
PMID: 35008804
Pulmonary hypertension is a serious clinical condition characterised by increased pulmonary arterial pressure. This can lead to right ventricular failure which can be fatal. Connexins are gap junction-forming membrane proteins...
3.
Lightbody R, Taylor J, Dempsie Y, Graham A
Biochim Biophys Acta Mol Cell Biol Lipids
. 2021 Jul;
1866(11):159005.
PMID: 34274506
Accumulation of excess cholesterol and cholesteryl ester in macrophage 'foam' cells within the arterial intima characterises early 'fatty streak' atherosclerotic lesions, and is accompanied by epigenetic changes, including altered expression...
4.
Lightbody R, Taylor J, Dempsie Y, Graham A
World J Cardiol
. 2020 Aug;
12(7):303-333.
PMID: 32843934
Accumulation of macrophage "foam" cells, laden with cholesterol and cholesteryl ester, within the intima of large arteries, is a hallmark of early "fatty streak" lesions which can progress to complex,...
5.
McNair A, Wilson K, Martin P, Welsh D, Dempsie Y
Pulm Circ
. 2020 Jul;
10(3):2045894020937134.
PMID: 32670564
Pulmonary hypertension (PH) is a disease associated with vasoconstriction and remodelling of the pulmonary vasculature. Pulmonary artery fibroblasts (PAFs) play an important role in hypoxic-induced remodelling. Connexin 43 (Cx43) is...
6.
Htet M, Nally J, Shaw A, Foote B, Martin P, Dempsie Y
Int J Mol Sci
. 2018 Jun;
19(7).
PMID: 29954114
Pulmonary arterial hypertension (PAH) is a chronic condition characterized by vascular remodeling and increased vaso-reactivity. PAH is more common in females than in males (~3:1). Connexin (Cx)43 has been shown...
7.
Dempsie Y, Martin P, Upton P
Biochem Soc Trans
. 2015 May;
43(3):524-9.
PMID: 26009202
Pulmonary arterial hypertension (PAH) is a complex, multi-factorial disorder characterized by both constriction and remodelling of the distal pulmonary vasculature. This leads to increased pulmonary pressures and eventually right heart...
8.
Wright A, Ewart M, Mair K, Nilsen M, Dempsie Y, Loughlin L, et al.
Cardiovasc Res
. 2015 Mar;
106(2):206-16.
PMID: 25765937
Aims: Pulmonary arterial hypertension (PAH) occurs more frequently in women with mutations in bone morphogenetic protein receptor type 2 (BMPR2) and dysfunctional BMPR2 signalling underpinning heritable PAH. We have previously...
9.
Grant J, Morecroft I, Dempsie Y, Van Rooij E, MacLean M, Baker A
Pulm Circ
. 2014 Jul;
3(4):840-50.
PMID: 25006399
MicroRNAs are small noncoding RNAs involved in the regulation of gene expression and have recently been implicated in the development of pulmonary arterial hypertension (PAH). Previous work has established that...
10.
White K, Dempsie Y, Caruso P, Wallace E, McDonald R, Stevens H, et al.
Hypertension
. 2014 Apr;
64(1):185-94.
PMID: 24732886
Pulmonary endothelial cell apoptosis is a transient, yet defining pathogenic event integral to the onset of many pulmonary vascular diseases such as pulmonary hypertension (PH). However, there is a paucity...