Yuval Samuni
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Explore the profile of Yuval Samuni including associated specialties, affiliations and a list of published articles.
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25
Citations
746
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Recent Articles
11.
Samuni Y, Samuni U, Goldstein S
Biochim Biophys Acta
. 2012 May;
1820(10):1560-6.
PMID: 22634736
Background: The pharmacological effects of hydroxamic acids (RC(O)NHOH, HX) are partially attributed to their ability to serve as HNO and/or NO donors under oxidative stress. Given the development and use...
12.
Yin H, Nguyen C, Samuni Y, Uede T, Peck A, Chiorini J
Arthritis Res Ther
. 2012 Feb;
14(1):R40.
PMID: 22369699
Introduction: Cytotoxic T-lymphocyte antigen 4 (CTLA-4) is a key negative costimulatory molecule that displays a wide range of anti-inflammatory properties and is currently approved to treat rheumatoid arthritis as a...
13.
Samuni Y, Baum B
Biochim Biophys Acta
. 2011 Jul;
1812(11):1515-21.
PMID: 21763423
In vivo gene delivery has long been seen as providing opportunities for the development of novel treatments for disorders refractory to existing therapies. Over the last two decades, salivary glands...
14.
Samuni Y, Cook J, Choudhuri R, DeGraff W, Sowers A, Krishna M, et al.
Free Radic Biol Med
. 2010 Jun;
49(4):667-73.
PMID: 20561604
Obesity is highly associated with an increased risk of serious health conditions including hypertension, cardiovascular disease, diabetes, and cancer. Changes in redox status with increased oxidative stress have been linked...
15.
Samuni U, Samuni Y, Goldstein S
J Am Chem Soc
. 2010 May;
132(24):8428-32.
PMID: 20504018
A better understanding of the origins of NO and HNO and their activities and biological functions requires accurate methods for their detection and quantification. The unique reaction of NO with...
16.
Samuni Y, Ishii H, Hyodo F, Samuni U, Krishna M, Goldstein S, et al.
Free Radic Biol Med
. 2010 Mar;
48(11):1559-63.
PMID: 20211249
Geldanamycin (GM), a benzoquinone ansamycin antibiotic, is a natural product inhibitor of Hsp90 with potent and broad anti-cancer properties. Because of its adverse effects on liver, its less toxic derivatives...
17.
Samuni Y, Flores-Santana W, Krishna M, Mitchell J, Wink D
Free Radic Biol Med
. 2009 May;
47(4):419-23.
PMID: 19447172
Suberoylanilide hydroxamic acid (SAHA, vorinostat, Zolinza) is the lead compound of a new class of histone deacetylase (HDAC) inhibitors used as anticancer drugs that have been shown to affect multiple...
18.
Samuni Y, Zheng C, Cawley N, Cotrim A, Loh Y, Baum B
Biochem Biophys Res Commun
. 2008 Jun;
373(1):136-9.
PMID: 18544341
Neuroendocrine and exocrine cells secrete proteins in either a constitutive manner or via the regulated secretory pathway (RSP), but the specific sorting mechanisms involved are not fully understood. After gene...
19.
Casap N, Alterman M, Sharon G, Samuni Y
J Oral Maxillofac Surg
. 2008 Apr;
66(5):878-81.
PMID: 18423274
Purpose: To evaluate the effect of informed consent on stress levels associated with removal of impacted mandibular third molars. Patients And Methods: A total of 60 patients scheduled for extraction...
20.
Casap N, Nimri S, Ziv E, Sela J, Samuni Y
Clin Oral Implants Res
. 2008 Mar;
19(5):458-64.
PMID: 18371104
Objectives: Dental implants are routinely used with high success rates in generally healthy individuals. In contrast, their use in patients with uncontrolled diabetes mellitus (DM) remains controversial as altered bone...