Yutaka Sashida
Overview
Explore the profile of Yutaka Sashida including associated specialties, affiliations and a list of published articles.
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Articles
44
Citations
691
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Recent Articles
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Yamamoto Y, Shioda N, Han F, Moriguchi S, Nakajima A, Yokosuka A, et al.
Brain Res
. 2009 Aug;
1295:218-29.
PMID: 19646972
Decreased cerebral blood flow causes cognitive impairments and neuronal injury in the progressive age-related neurodegenerative disorders such as Alzheimer's disease (AD) and vascular dementia. In the present study, we for...
3.
Kunimasa K, Kuranuki S, Matsuura N, Iwasaki N, Ikeda M, Ito A, et al.
Bioorg Med Chem Lett
. 2009 Mar;
19(7):2062-4.
PMID: 19268587
Adiponectin, an adipocyte-derived protein with insulin-sensitizing, anti-diabetic and anti-atherogenic activities, is known to be induced during adipocyte differentiation. Nobiletin, a citrus polymethoxy flavonoid, was found to induce the differentiation of...
4.
Onozuka H, Nakajima A, Matsuzaki K, Shin R, Ogino K, Saigusa D, et al.
J Pharmacol Exp Ther
. 2008 Jun;
326(3):739-44.
PMID: 18544674
Increasing evidence suggests that the elevation of beta-amyloid (Abeta) peptides in the brain is central to the pathogenesis of Alzheimer's disease (AD). Our recent studies have demonstrated that nobiletin, a...
5.
Matsuzaki K, Miyazaki K, Sakai S, Yawo H, Nakata N, Moriguchi S, et al.
Eur J Pharmacol
. 2007 Nov;
578(2-3):194-200.
PMID: 17976577
Nobiletin isolated from citrus peels prevents bulbectomy- and amyloid-beta protein-induced memory impairment in rodents. In the present study, using combined methods of biochemistry and electrophysiology, we examined the effects of...
6.
Nakajima A, Yamakuni T, Haraguchi M, Omae N, Song S, Kato C, et al.
J Pharmacol Sci
. 2007 Sep;
105(1):122-6.
PMID: 17895593
We have recently reported that nobiletin, a citrus flavonoid, improves impaired memory in olfactory-bulbectomized (OBX) mice, which have been widely utilized as a useful paradigm that shares some major clinical...
7.
Nakajima A, Yamakuni T, Matsuzaki K, Nakata N, Onozuka H, Yokosuka A, et al.
J Pharmacol Exp Ther
. 2007 Feb;
321(2):784-90.
PMID: 17289833
Recent studies have indicated that learning-induced activation of extracellular signal-regulated kinase (ERK) signaling via N-methyl-D-aspartate (NMDA) receptors is required for consolidation of the resultant learning. These findings raise an idea...
8.
Mimaki Y, Nadaoka I, Yasue M, Ohtake Y, Ikeda M, Watanabe K, et al.
J Nat Prod
. 2006 May;
69(5):829-32.
PMID: 16724852
Two new cycloartane glycosides, named neocimicigenosides A (1) and B (2), were isolated from the rhizomes of Cimicifuga racemosa. The structures of 1 and 2 were determined on the basis...
9.
Matsuzaki K, Yamakuni T, Hashimoto M, Haque A, Shido O, Mimaki Y, et al.
Neurosci Lett
. 2006 Apr;
400(3):230-4.
PMID: 16581185
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive and memory deterioration. Production and accumulation of beta-amyloid peptide (Abeta) is central to the pathogenesis of AD. Recent studies...
10.
Nagase H, Omae N, Omori A, Nakagawasai O, Tadano T, Yokosuka A, et al.
Biochem Biophys Res Commun
. 2005 Oct;
337(4):1330-6.
PMID: 16253614
cAMP response element (CRE) transcription is dysregulated in neurodegenerative disorders in the central nervous system (CNS), including polyglutamine diseases. As the first step to find natural compounds with protective action...