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Yusuke Murase

Explore the profile of Yusuke Murase including associated specialties, affiliations and a list of published articles. Areas
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Articles 24
Citations 340
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Recent Articles
1.
Higashi T, Kimura M, Kato Y, Hattori K, Kawajiri M, Murase Y, et al.
Anticancer Res . 2024 Oct; 44(11):5051-5058. PMID: 39477298
Background/aim: Cancer-associated systemic inflammatory response is a pivotal indicator of tumor progression and prognosis in various cancers. "Lymphocyte × albumin (LA)" is a prognostic inflammatory marker in rectal cancer. This...
2.
Murase Y, Yokogawa R, Yabuta Y, Nagano M, Katou Y, Mizuyama M, et al.
Nature . 2024 May; 631(8019):170-178. PMID: 38768632
Epigenetic reprogramming resets parental epigenetic memories and differentiates primordial germ cells (PGCs) into mitotic pro-spermatogonia or oogonia. This process ensures sexually dimorphic germ cell development for totipotency. In vitro reconstitution...
3.
Murase Y, Hosoya K, Sato T, Kim S, Okumura M
Oncol Rep . 2022 Jan; 47(4). PMID: 35088890
The phosphatidylinositol 3‑kinase/mammalian target of rapamycin (PI3K/mTOR) signaling pathway is a therapeutic target for various types of human tumors, and dual PI3K/mTOR inhibitors demonstrate antitumor activities in both preclinical and...
4.
Yokobayashi S, Yabuta Y, Nakagawa M, Okita K, Hu B, Murase Y, et al.
Cell Rep . 2021 Nov; 37(5):109909. PMID: 34731633
Human induced pluripotent stem cells (hiPSCs) show variable differentiation potential due to their epigenomic heterogeneity, whose extent/attributes remain unclear, except for well-studied elements/chromosomes such as imprints and the X chromosomes....
5.
Sung K, Hosoya K, Murase Y, Deguchi T, Kim S, Sunaga T, et al.
Vet Comp Oncol . 2021 Oct; 20(1):324-335. PMID: 34719098
Cancer stem-like cells (CSCs) cause treatment failure in various tumours; however, establishing CSC-targeted therapies has been hampered by difficulties in the identification and isolation of this small sub-population of cells....
6.
Deguchi T, Hosoya K, Kim S, Murase Y, Yamamoto K, Bo T, et al.
Mol Ther Oncolytics . 2021 Sep; 22:143-151. PMID: 34514095
Metformin has many anti-cancer effects, alone or in combination with radiation. However, the mechanism underlying its radio-sensitized effect is still unclear, especially for cancer stem-like cells (CSCs). Here, the radio-sensitized...
7.
Ishikura Y, Ohta H, Sato T, Murase Y, Yabuta Y, Kojima Y, et al.
Cell Stem Cell . 2021 Sep; 28(12):2167-2179.e9. PMID: 34496297
Mammalian male germ-cell development consists of three distinct phases: primordial germ cell (PGC) development, male germ-cell specification for spermatogonium development, and ensuing spermatogenesis. Here, we show an in vitro reconstitution...
8.
Kojima Y, Yamashiro C, Murase Y, Yabuta Y, Okamoto I, Iwatani C, et al.
Life Sci Alliance . 2021 Feb; 4(5). PMID: 33608411
The in vitro reconstitution of human germ-cell development provides a robust framework for clarifying key underlying mechanisms. Here, we explored transcription factors (TFs) that engender the germ-cell fate in their...
9.
Hayashi H, Matsuhisa M, Murase Y, Sano H, Nishio K, Kumazawa I
Int J Surg Case Rep . 2021 Jan; 78:342-346. PMID: 33388515
Introduction: Intestinal malrotation is a congenital anatomical anomaly resulting from abnormal midgut rotation. Many cases occur during childhood and present with intestinal obstruction and midgut volvulus. Intestinal malrotation rarely occurs...
10.
Ohta H, Yabuta Y, Kurimoto K, Nakamura T, Murase Y, Yamamoto T, et al.
Biol Reprod . 2020 Oct; 104(2):344-360. PMID: 33079185
Primordial germ cells (PGCs) are the founding population of the germ cell lineage that undergo a multistep process to generate spermatozoa or oocytes. Establishing an appropriate culture system for PGCs...