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Yurii Stepanovskyy

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Citations 423
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Recent Articles
1.
Bastard P, Vazquez S, Liu J, Laurie M, Wang C, Gervais A, et al.
Sci Immunol . 2022 Jul; 8(90):eabp8966. PMID: 35857576
Life-threatening "breakthrough" cases of critical COVID-19 are attributed to poor or waning antibody (Ab) response to SARS-CoV-2 vaccines in individuals already at risk. Preexisting auto-Abs neutralizing type I IFNs underlie...
2.
Manry J, Bastard P, Gervais A, Le Voyer T, Rosain J, Philippot Q, et al.
Proc Natl Acad Sci U S A . 2022 May; 119(21):e2200413119. PMID: 35576468
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection fatality rate (IFR) doubles with every 5 y of age from childhood onward. Circulating autoantibodies neutralizing IFN-α, IFN-ω, and/or IFN-β are found...
3.
Manry J, Bastard P, Gervais A, Le Voyer T, Rosain J, Philippot Q, et al.
Res Sq . 2022 Jan; PMID: 35043109
SARS-CoV-2 infection fatality rate (IFR) doubles with every five years of age from childhood onward. Circulating autoantibodies neutralizing IFN-α, IFN-ω, and/or IFN-β are found in ~20% of deceased patients across...
4.
Bastard P, Gervais A, Le Voyer T, Rosain J, Philippot Q, Manry J, et al.
Sci Immunol . 2021 Aug; 6(62. PMID: 34413139
Circulating autoantibodies (auto-Abs) neutralizing high concentrations (10 ng/mL, in plasma diluted 1 to 10) of IFN-α and/or -ω are found in about 10% of patients with critical COVID-19 pneumonia, but...