Yuri P Rubtsov
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Explore the profile of Yuri P Rubtsov including associated specialties, affiliations and a list of published articles.
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11
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2623
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Recent Articles
1.
Stepanova V, Volkov D, Osipova D, Wang W, Hou Y, Pershin D, et al.
Mol Ther Oncol
. 2025 Jan;
32(3):200843.
PMID: 39822756
Hematopoietic stem cell transplantation (HSCT) is widely used to treat patients with life-threatening hematologic and immune system disorders. Current nontargeted chemo-/radiotherapy conditioning regimens cause tissue injury and induce an array...
2.
Lomakin Y, Ovchinnikova L, Terekhov S, Dzhelad S, Yaroshevich I, Mamedov I, et al.
Commun Biol
. 2024 Jul;
7(1):842.
PMID: 38987383
Identifying high-affinity antibodies in human serum is challenging due to extremely low number of circulating B cells specific to the desired antigens. Delays caused by a lack of information on...
3.
Stepanov A, Kalinin R, Shipunova V, Zhang D, Xie J, Rubtsov Y, et al.
Proc Natl Acad Sci U S A
. 2022 Nov;
119(46):e2210562119.
PMID: 36343224
The development of chimeric antigen receptor (CAR) T cell therapy has become a critical milestone in modern oncotherapy. Despite the remarkable in vitro effectiveness, the problem of safety and efficacy...
4.
Rubtsov Y, Niec R, Josefowicz S, Li L, Darce J, Mathis D, et al.
Science
. 2010 Oct;
329(5999):1667-71.
PMID: 20929851
Tissue maintenance and homeostasis can be achieved through the replacement of dying cells by differentiating precursors or self-renewal of terminally differentiated cells or relies heavily on cellular longevity in poorly...
5.
Rubtsov Y, Rasmussen J, Chi E, Fontenot J, Castelli L, Ye X, et al.
Immunity
. 2008 Apr;
28(4):546-58.
PMID: 18387831
The regulatory T (Treg) cells restrain immune responses through suppressor-function elaboration that is dependent upon expression of the transcription factor Foxp3. Despite a critical role for Treg cells in maintaining...
6.
Zhou L, Lopes J, Chong M, Ivanov I, Min R, Victora G, et al.
Nature
. 2008 Mar;
453(7192):236-40.
PMID: 18368049
T helper cells that produce IL-17 (T(H)17 cells) promote autoimmunity in mice and have been implicated in the pathogenesis of human inflammatory diseases. At mucosal surfaces, T(H)17 cells are thought...
7.
Rubtsov Y, Rudensky A
Nat Rev Immunol
. 2007 May;
7(6):443-53.
PMID: 17525753
In the immune system, transforming growth factor-beta (TGFbeta) affects multiple cell lineages by either promoting or opposing their differentiation, survival and proliferation. Understanding the cellular mechanisms of TGFbeta-mediated regulation is...
8.
Henderson Jr W, Chi E, Bollinger J, Tien Y, Ye X, Castelli L, et al.
J Exp Med
. 2007 Apr;
204(4):865-77.
PMID: 17403936
Arachidonic acid metabolites, the eicosanoids, are key mediators of allergen-induced airway inflammation and remodeling in asthma. The availability of free arachidonate in cells for subsequent eicosanoid biosynthesis is controlled by...
9.
Karapetian R, Evstafieva A, Abaeva I, Chichkova N, Filonov G, Rubtsov Y, et al.
Mol Cell Biol
. 2005 Jan;
25(3):1089-99.
PMID: 15657435
Animal cells counteract oxidative stress and electrophilic attack through coordinated expression of a set of detoxifying and antioxidant enzyme genes mediated by transcription factor Nrf2. In unstressed cells, Nrf2 appears...
10.
Chichkova N, Kim S, Titova E, Kalkum M, Morozov V, Rubtsov Y, et al.
Plant Cell
. 2003 Dec;
16(1):157-71.
PMID: 14660804
To test the hypothesis that caspase-like proteases exist and are critically involved in the implementation of programmed cell death (PCD) in plants, a search was undertaken for plant caspases activated...