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Yuquan Wen

Explore the profile of Yuquan Wen including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 514
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Recent Articles
1.
Rubin G, Wen Y, Loop M, Kraft T
Int J Mol Sci . 2022 Apr; 23(8). PMID: 35456959
The full-field ERG is useful for index rod- or cone-mediated retinal function in rodent models of retinal degeneration. However, the relationship between the ERG response amplitudes and visually guided behavior,...
2.
Ryals R, Andrews M, Datta S, Coyner A, Fischer C, Wen Y, et al.
Invest Ophthalmol Vis Sci . 2017 Mar; 58(3):1378-1386. PMID: 28253400
Purpose: Prospective treatments for age-related macular degeneration and inherited retinal degenerations are commonly evaluated in the Royal College of Surgeons (RCS) rat before translation into clinical application. Historically, retinal thickness...
3.
Coyner A, Ryals R, Ku C, Fischer C, Patel R, Datta S, et al.
PLoS One . 2016 Jul; 11(7):e0159776. PMID: 27447833
Purpose: To assess the neuroprotective effects of flibanserin (formerly BIMT-17), a dual 5-HT1A agonist and 5-HT2A antagonist, in a light-induced retinopathy model. Methods: Albino BALB/c mice were injected intraperitoneally with...
4.
Scholl H, Moore A, Koenekoop R, Wen Y, Fishman G, van den Born L, et al.
PLoS One . 2015 Dec; 10(12):e0143846. PMID: 26656277
Unlabelled: Restoring vision in inherited retinal degenerations remains an unmet medical need. In mice exhibiting a genetically engineered block of the visual cycle, vision was recently successfully restored by oral...
5.
Wen Y, Birch D
Transl Vis Sci Technol . 2015 Oct; 4(5):8. PMID: 26448901
Purpose: To determine whether the degree of change in Goldmann visual fields (GVFs) following oral administration of QLT091001 was related to baseline measures of retinal structure. Methods: Oral QLT091001 was...
6.
Tullis B, Ryals R, Coyner A, Gale M, Nicholson A, Ku C, et al.
Invest Ophthalmol Vis Sci . 2015 Jul; 56(8):4560-9. PMID: 26200496
Purpose: To determine if sarpogrelate, a selective 5-HT2A receptor antagonist, is protective against light-induced retinopathy in BALB/c mice. Methods: BALB/c mice were dosed intraperitoneally with 5, 15, 30, 40, or...
7.
Yang P, Michaels K, Courtney R, Wen Y, Greninger D, Reznick L, et al.
JAMA Ophthalmol . 2014 Mar; 132(7):823-31. PMID: 24676353
Importance: While older children and adults with achromatopsia have been studied, less is known of young children with achromatopsia. Objectives: To characterize the macular and foveal architecture of patients with...
8.
Birch D, Locke K, Wen Y, Locke K, Hoffman D, Hood D
JAMA Ophthalmol . 2013 Jul; 131(9):1143-50. PMID: 23828615
Importance: Determining the annual rate of change in the width of the inner segment ellipsoid zone (EZ; ie, inner/outer segment border) in the context of short-term variability should allow us...
9.
Yanni S, Wang J, Cheng C, Locke K, Wen Y, Birch D, et al.
Am J Ophthalmol . 2012 Nov; 155(2):354-360.e1. PMID: 23127751
Purpose: To establish a normative database of peripapillary retinal nerve fiber layer (RNFL) thickness, macular thickness, and retinal layer thickness in healthy North American children, using spectral-domain optical coherence tomography...
10.
Pennesi M, Michaels K, Magee S, Maricle A, Davin S, Garg A, et al.
Invest Ophthalmol Vis Sci . 2012 May; 53(8):4644-56. PMID: 22562504
Purpose: We characterize the in vivo changes over time in the retinal structure of wild-type mice alongside two lines of mice deficient in the β-subunit of phosphodiesterase (rd1 and rd10...