Yuqiang Ge
Overview
Explore the profile of Yuqiang Ge including associated specialties, affiliations and a list of published articles.
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10
Citations
448
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Recent Articles
1.
Zhang Y, Sands J, Kohan D, Nelson R, Martin C, Carlson N, et al.
Am J Physiol Renal Physiol
. 2008 Oct;
295(6):F1715-24.
PMID: 18829742
Osmotic reabsorption of water through aquaporin-2 (AQP2) in the inner medulla is largely dependent on the urea concentration gradients generated by urea transporter (UT) isoforms. Vasopressin (AVP) increases expression of...
2.
Ge Y, Bagnall A, Stricklett P, Webb D, Kotelevtsev Y, Kohan D
Am J Physiol Renal Physiol
. 2008 Sep;
295(6):F1635-40.
PMID: 18784261
The collecting duct (CD) endothelin (ET) system regulates blood pressure (BP) and Na excretion. CD-specific knockout (KO) of ET-1 causes hypertension, CD-specific KO of the ETA receptor does not alter...
3.
Ge Y, Huang Y, Kohan D
Can J Physiol Pharmacol
. 2008 Jun;
86(6):329-36.
PMID: 18516095
Renal collecting duct (CD)-specific knockout of endothelin-1 (ET-1) causes hypertension and impaired Na excretion. A previous study noted failure to suppress the renin-angiotensin-aldosterone axis in these knockout (KO) mice, hence...
4.
Schneider M, Ge Y, Pollock D, Pollock J, Kohan D
Hypertension
. 2008 Apr;
51(6):1605-10.
PMID: 18391099
Mice with a collecting duct-specific deletion of endothelin-1 are hypertensive and have impaired Na excretion. Because endothelin-1 activates NO synthase (NOS) in the collecting duct, we hypothesized that impaired renal...
5.
Ge Y, Strait K, Stricklett P, Yang T, Kohan D
Am J Physiol Renal Physiol
. 2007 Oct;
293(6):F1805-10.
PMID: 17913832
Collecting duct (CD)-derived endothelin-1 (ET-1) exerts natriuretic, diuretic, and hypotensive effects. In vitro studies have implicated cyclooxygenase (COX) metabolites, and particularly PGE(2), as important mediators of CD ET-1 effects. However,...
6.
Ge Y, Bagnall A, Stricklett P, Strait K, Webb D, Kotelevtsev Y, et al.
Am J Physiol Renal Physiol
. 2006 Jul;
291(6):F1274-80.
PMID: 16868309
Collecting duct (CD)-derived endothelin-1 (ET-1) inhibits renal Na reabsorption and its deficiency increases blood pressure (BP). The role of CD endothelin B (ETB) receptors in mediating these effects is unknown....
7.
Ge Y, Stricklett P, Hughes A, Yanagisawa M, Kohan D
Am J Physiol Renal Physiol
. 2005 Jun;
289(4):F692-8.
PMID: 15928212
Collecting duct (CD)-specific knockout (KO) of endothelin-1 (ET-1) causes hypertension, impaired ability to excrete a Na load, and enhanced CD sensitivity to the hydrosmotic effects of vasopressin (AVP). CD express...
8.
Ge Y, Ahn D, Stricklett P, Hughes A, Yanagisawa M, Verbalis J, et al.
Am J Physiol Renal Physiol
. 2005 Jan;
288(5):F912-20.
PMID: 15632412
In vitro studies suggest that endothelin-1 (ET-1) inhibits vasopressin (AVP)-stimulated water permeability in the collecting duct (CD). To evaluate the role of CD-derived ET-1 in regulating renal water metabolism, the...
9.
Ahn D, Ge Y, Stricklett P, Gill P, Taylor D, Hughes A, et al.
J Clin Invest
. 2004 Aug;
114(4):504-11.
PMID: 15314687
In vitro studies suggest that collecting duct-derived (CD-derived) endothelin-1 (ET-1) can regulate renal Na reabsorption; however, the physiologic role of CD-derived ET-1 is unknown. Consequently, the physiologic effect of selective...
10.
Ge Y, Xu Y, Liao L
Ren Fail
. 2002 Mar;
24(1):1-9.
PMID: 11921692
To guide the administration of fat emulsion in the nutritional support of acute renal failure (ARF), pharmacokinetic analysis with an one-compartment open model after bolus intravenous injection was performed to...