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Yunmin Li

Explore the profile of Yunmin Li including associated specialties, affiliations and a list of published articles. Areas
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Articles 23
Citations 425
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Recent Articles
1.
Kennedy P, Arvindam U, Phung S, Ettestad B, Feng X, Li Y, et al.
Sci Adv . 2024 Oct; 10(44):eadn1849. PMID: 39475618
Limited oxygen (hypoxia) in solid tumors poses a challenge to successful immunotherapy with natural killer (NK) cells. NK cells have impaired cytotoxicity when cultured in hypoxia (1% oxygen) but not...
2.
Kido T, Li Y, Tanaka Y, Dahiya R, Lau Y
Oncotarget . 2019 Mar; 10(15):1491-1506. PMID: 30863497
TSPX is a tumor suppressor gene located at Xp11.22, a prostate cancer susceptibility locus. It is ubiquitously expressed in most tissues but frequently downregulated in various cancers, including lung, brain,...
3.
Lau Y, Li Y, Kido T
Asian J Androl . 2018 Jul; 21(3):260-269. PMID: 29974883
The Y-located testis-specific protein Y-encoded (TSPY) and its X-homologue TSPX originated from the same ancestral gene, but act as a proto-oncogene and a tumor suppressor gene, respectively. TSPY has specialized...
4.
Li Y, Zhang D, Qiu Y, Kido T, Lau Y
Hum Mol Genet . 2017 Feb; 26(5):901-912. PMID: 28169398
The gonadoblastoma gene, testis-specific protein Y-encoded (TSPY), on the Y chromosome and its X-homologue, TSPX, are cell cycle regulators and function as a proto-oncogene and a tumor suppressor respectively in...
5.
Li Y, Kido T, Garcia-Barcelo M, Tam P, Tabatabai Z, Lau Y
Hum Mol Genet . 2014 Oct; 24(3):685-97. PMID: 25267720
The Hirschsprung disease (HSCR) is a complex congenital disorder, arising from abnormalities in enteric nervous system (ENS) development. There is a gender disparity among the patients, with the male to...
6.
Li Y, Zheng M, Lau Y
Cell Rep . 2014 Aug; 8(3):723-33. PMID: 25088423
Male sex determination is mediated sequentially by sex-determining region Y (SRY) and related SRY-box 9 (SOX9) transcription factors. To understand the gene regulatory hierarchy for SRY and SOX9, a series...
7.
Kido T, Lo R, Li Y, Lee J, Tabatabai Z, Ng I, et al.
Hum Pathol . 2014 Jul; 45(9):1847-58. PMID: 25017435
There is a significant sex disparity favoring males among hepatocellular carcinoma (HCC) patients. Although various risk factors have been identified, the exact etiology of such sexual dimorphism(s) in HCC is...
8.
Zheng M, Li Y, Lau Y
Methods Mol Biol . 2013 Aug; 1067:185-202. PMID: 23975793
Chromatin immunoprecipitation and hybridization of high-density promoter microarray (ChIP-chip) is a powerful strategy to identify target genes for specific transcription factors and other DNA-binding nuclear proteins in a genome-wide manner....
9.
Li Y, Taketo T, Lau Y
Methods Mol Biol . 2011 Dec; 825:3-16. PMID: 22144232
Gonadal sex differentiation is an important developmental process, in which a bipotential primordial gonad undergoes two distinct pathways, i.e., testicular and ovarian differentiation, dependent on its genetic sex. Techniques of...
10.
Lau Y, Li Y, Kido T
Syst Biol Reprod Med . 2011 Jan; 57(1-2):27-34. PMID: 21204751
The gonadoblastoma locus on the human Y chromosome (GBY) is postulated to serve normal functions in spermatogenesis, but could exert oncogenic properties in predisposing susceptible germ cells to tumorigenesis in...