Yun-Bo Guo
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Explore the profile of Yun-Bo Guo including associated specialties, affiliations and a list of published articles.
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Articles
10
Citations
175
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0
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Recent Articles
1.
Zhao Y, Guo Y, Fan X, Yang H, Zhou P, Chen Z, et al.
Sci Bull (Beijing)
. 2023 Jan;
62(19):1295-1303.
PMID: 36659291
The elementary Ca release events, Ca sparks, has been found for a quarter of century. However, the molecular regulation of the spark generator, the ryanodine receptor (RyR) on the sarcoplasmic...
2.
Yang L, Li R, Xiang B, Li Y, Wang L, Guo Y, et al.
Proc Natl Acad Sci U S A
. 2021 Mar;
118(14).
PMID: 33785600
The contraction of heart cells is controlled by the intermolecular signaling between L-type Ca channels (LCCs) and ryanodine receptors (RyRs), and the nanodistance between them depends on the interaction between...
3.
Yang H, Zhou P, Wang L, Zhao Y, Ren Y, Guo Y, et al.
Cardiovasc Res
. 2020 Feb;
116(13):2069-2080.
PMID: 32031586
Aims: β-adrenergic receptors (βARs) play pivotal roles in regulating cardiac excitation-contraction (E-C) coupling. Global signalling of β1ARs up-regulates both the influx of Ca2+ through sarcolemmal L-type Ca2+ channels (LCCs) and...
4.
Zhao Y, Guo Y, Gu L, Fan X, Yang H, Chen Z, et al.
Cardiovasc Res
. 2017 Jan;
113(3):332-342.
PMID: 28077437
Aims: The heart contraction is controlled by the Ca2+-induced Ca2+ release (CICR) between L-type Ca2+ channels and ryanodine receptors (RyRs). The FK506-binding protein FKBP12.6 binds to RyR subunits, but its...
5.
Li R, Tao J, Guo Y, Wu H, Liu R, Bai Y, et al.
Circ Res
. 2013 Jan;
112(4):601-5.
PMID: 23307820
Rationale: During the transition from compensated hypertrophy to heart failure, the signaling between L-type Ca(2+) channels in the cell membrane/T-tubules and ryanodine receptors in the sarcoplasmic reticulum becomes defective, partially...
6.
Xu M, Wu H, Li R, Zhang H, Wang M, Tao J, et al.
Circ Res
. 2012 Aug;
111(7):837-41.
PMID: 22891046
Rationale: Failing cardiomyocytes exhibit decreased efficiency of excitation-contraction (E-C) coupling. The downregulation of junctophilin-2 (JP2), a protein anchoring the sarcoplasmic reticulum to T-tubules, has been identified as a major mechanism...
7.
Sun X, Guo Y, Liu N, Ma L, Deng Q
Nan Fang Yi Ke Da Xue Xue Bao
. 2011 Apr;
31(4):610-4.
PMID: 21515453
Objective: To design a platform for microarray data analysis and processing in the browser/server mode running in Linux operating system. Methods: Based on the Apache HTTP server, the platform, programmed...
8.
Liu N, Guo Y, Sun X, Ma L, Deng Q
Nan Fang Yi Ke Da Xue Xue Bao
. 2010 Feb;
30(2):219-23.
PMID: 20159684
Objective: To design a versatile genome comparison and visualization platform based on browser/server mode supported by a local server. Methods: The server of the platform was Apache HTTP server. Perl...
9.
Zhou P, Zhao Y, Guo Y, Xu S, Bai S, Lakatta E, et al.
Proc Natl Acad Sci U S A
. 2009 Oct;
106(42):18028-33.
PMID: 19815510
As the most prototypical G protein-coupled receptor, beta-adrenergic receptor (betaAR) regulates the pace and strength of heart beating by enhancing and synchronizing L-type channel (LCC) Ca(2+) influx, which in turn...
10.
Liu W, Chen J, Ren F, Guo Y, Yan X, Liu Y
Di Yi Jun Yi Da Xue Xue Bao
. 2005 Apr;
25(4):413-5.
PMID: 15837641
Objective: To establish a method by high-performance liquid chromatography (HPLC) for determining the concentration of magnetic mitomycin C-polybutylcyanoacrylate nanoparticles in mouse plasma. Methods: Chromatography was performed on a LiChroCART C18...