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Yuma Osako

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Articles 12
Citations 34
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Recent Articles
1.
Saito Y, Osako Y, Murayama M
Microscopy (Oxf) . 2025 Feb; PMID: 39953796
The brain is an intricate neuronal network that orchestrates our thoughts, emotions, and actions through dynamic interactions between neurons. If we could record the activity of all neurons simultaneously in...
2.
Saito Y, Osako Y, Odagawa M, Oisi Y, Matsubara C, Kato S, et al.
Neuron . 2025 Jan; PMID: 39884277
Emotional arousal plays a critical role in determining what is remembered from experiences. It is hypothesized that activation of the amygdala by emotional stimuli enhances memory consolidation in its downstream...
3.
Leow Y, Barlowe A, Luo C, Osako Y, Jazayeri M, Sur M
bioRxiv . 2024 Nov; PMID: 39605622
Prior expectations guide attention and support perceptual filtering for efficient processing during decision-making. Here we show that during a visual discrimination task, mice adaptively use prior stimulus history to guide...
4.
Park J, Sipe G, Tang X, Ojha P, Fernandes G, Leow Y, et al.
bioRxiv . 2024 Nov; PMID: 39605420
Astrocytes, which are increasingly recognized as pivotal constituents of brain circuits governing a wide range of functions, express GABA transporter 3 (Gat3), an astrocyte-specific GABA transporter responsible for maintenance of...
5.
Drummond G, Natesan A, Celotto M, Shih J, Ojha P, Osako Y, et al.
bioRxiv . 2024 Nov; PMID: 39484425
Updating behavior based on feedback from the environment is a crucial means by which organisms learn and develop optimal behavioral strategies. Norepinephrine (NE) release from the locus coeruleus (LC) has...
6.
Osaki T, Delepine C, Osako Y, Kranz D, Levin A, Nelson C, et al.
bioRxiv . 2024 Aug; PMID: 39149328
Human cerebral organoids derived from induced pluripotent stem cells can recapture early developmental processes and reveal changes involving neurodevelopmental disorders. Mutations in the X-linked methyl-CpG binding protein 2 (MECP2) gene...
7.
Shiotani K, Tanisumi Y, Osako Y, Murata K, Hirokawa J, Sakurai Y, et al.
iScience . 2024 Feb; 27(2):108924. PMID: 38327778
Flavor plays a critical role in the pleasure of food. Flavor research has mainly focused on human subjects and revealed that many brain regions are involved in flavor perception. However,...
8.
Takamiya S, Shiotani K, Ohnuki T, Osako Y, Tanisumi Y, Yuki S, et al.
eNeuro . 2022 May; 9(3). PMID: 35551094
The activity of primary auditory cortex (A1) neurons is modulated not only by sensory inputs but also by other task-related variables in associative learning. However, it is unclear how A1...
9.
Takamiya S, Shiotani K, Ohnuki T, Osako Y, Tanisumi Y, Yuki S, et al.
Front Syst Neurosci . 2021 Sep; 15:718619. PMID: 34552474
The hippocampus is crucial for forming associations between environmental stimuli. However, it is unclear how neural activities of hippocampal neurons dynamically change during the learning process. To address this question,...
10.
Ohnuki T, Osako Y, Manabe H, Sakurai Y, Hirokawa J
Neurosci Res . 2021 Jul; 173:1-13. PMID: 34274406
The brain is organized into anatomically distinct structures consisting of a variety of projection neurons. While such evolutionarily conserved neural circuit organization underlies the innate ability of animals to swiftly...