Yulia Haim
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Explore the profile of Yulia Haim including associated specialties, affiliations and a list of published articles.
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29
Citations
442
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Recent Articles
1.
Lazarescu O, Ziv-Agam M, Haim Y, Hekselman I, Jubran J, Shneyour A, et al.
Nat Genet
. 2025 Jan;
57(2):413-426.
PMID: 39856219
Human adipose depots are functionally distinct. Yet, recent single-nucleus RNA sequencing (snRNA-seq) analyses largely uncovered overlapping or similar cell-type landscapes. We hypothesized that adipocyte subtypes, differentiation trajectories and/or intercellular communication...
2.
Sorek G, Haim Y, Chalifa-Caspi V, Lazarescu O, Ziv-Agam M, Hagemann T, et al.
iScience
. 2024 Jul;
27(7):110368.
PMID: 39071890
Deconvolution algorithms mostly rely on single-cell RNA-sequencing (scRNA-seq) data applied onto bulk RNA-sequencing (bulk RNA-seq) to estimate tissues' cell-type composition, with performance accuracy validated on deposited databases. Adipose tissues' cellular...
3.
Makarenkov N, Yoel U, Haim Y, Pincu Y, Bhandarkar N, Shalev A, et al.
Int J Mol Sci
. 2024 Jan;
25(2).
PMID: 38255963
Circulating miRNAs are increasingly being considered as biomarkers in various medical contexts, but the value of analyzing isomiRs (isoforms of canonical miRNA sequences) has not frequently been assessed. Here we...
4.
Pincu Y, Makarenkov N, Tsitrina A, Rosengarten-Levine M, Haim Y, Yoel U, et al.
Obesity (Silver Spring)
. 2023 Sep;
31(12):2986-2997.
PMID: 37746932
Objective: In obesity, adipocyte hypertrophy is detrimental to health, but its' interrelation with fibrosis in the visceral adipose tissue (VAT) depot remains unclear. Because VAT is less accessible via biopsy,...
5.
Makarenkov N, Haim Y, Yoel U, Pincu Y, Tarnovscki T, Liberty I, et al.
J Clin Endocrinol Metab
. 2023 Sep;
109(3):858-867.
PMID: 37713174
Context: The severity of visceral adipose tissue (VAT) inflammation in individuals with obesity is thought to signify obesity subphenotype(s) associated with higher cardiometabolic risk. Yet, this tissue is not accessible...
6.
Maixner N, Haim Y, Bluher M, Chalifa-Caspi V, Veksler-Lublinsky I, Makarenkov N, et al.
Cells
. 2022 Oct;
11(19).
PMID: 36231008
Up-regulated expression of transcription-factor E2F1 in human visceral adipose tissue (VAT) characterizes a dysmetabolic obesity sub-phenotype. An E2F1-miRNA network has been described in multiple cancers. Here we investigated whether elevated...
7.
Pincu Y, Yoel U, Haim Y, Makarenkov N, Maixner N, Shaco-Levy R, et al.
Front Endocrinol (Lausanne)
. 2022 May;
13:860799.
PMID: 35574032
Obesity is a heterogenous condition that affects the life and health of patients to different degrees and in different ways. Yet, most approaches to treat obesity are not currently prescribed,...
8.
Lahav R, Haim Y, Bhandarkar N, Levin L, Chalifa-Caspi V, Sarver D, et al.
Am J Physiol Endocrinol Metab
. 2021 Oct;
321(5):E702-E713.
PMID: 34632797
In chronic obesity, activated adipose tissue proinflammatory cascades are tightly linked to metabolic dysfunction. Yet, close temporal analyses of the responses to obesogenic environment such as high-fat feeding (HFF) in...
9.
Bhandarkar N, Lahav R, Maixner N, Haim Y, Wong G, Rudich A, et al.
Physiol Rep
. 2021 Sep;
9(18):e15044.
PMID: 34553504
In humans, exercise-induced thermogenesis is a markedly variable component of total energy expenditure, which had been acutely affected worldwide by COVID-19 pandemic-related lockdowns. We hypothesized that dietary macronutrient composition may...
10.
Goldstein N, Tsuneki H, Bhandarkar N, Aimaretti E, Haim Y, Kon K, et al.
Obesity (Silver Spring)
. 2021 Sep;
29(11):1857-1867.
PMID: 34472713
Objective: Orexin/hypocretin (Ox) and its receptors (OxR), a neuroendocrine system centrally regulating sleep/wakefulness, were implicated in the regulation of peripheral metabolism. It was hypothesized that human adipose tissue constitutes a...