Yukino Hatazawa
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Explore the profile of Yukino Hatazawa including associated specialties, affiliations and a list of published articles.
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18
Citations
356
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Recent Articles
1.
Oyabu M, Takigawa K, Mizutani S, Hatazawa Y, Fujita M, Ohira Y, et al.
FASEB J
. 2022 Jan;
36(2):e22152.
PMID: 35061305
Catabolic conditions, such as starvation, inactivity, and cancer cachexia, induce Forkhead box O (FOXO) transcription factor(s) expression and severe muscle atrophy via the induction of ubiquitin-proteasome system-mediated muscle proteolysis, resulting...
2.
Sugimoto T, Uchitomi R, Hatazawa Y, Miura S, Kamei Y
Biosci Biotechnol Biochem
. 2021 Feb;
85(3):579-586.
PMID: 33590008
PGC-1α expression increases in skeletal muscles during exercise and regulates the transcription of many target genes. In this study, we conducted a metabolomic analysis on the blood of transgenic mice...
3.
Nakai S, Oyabu M, Hatazawa Y, Akashi S, Kitamura T, Miura S, et al.
FEBS Open Bio
. 2020 May;
10(7):1373-1388.
PMID: 32433820
Peroxisome proliferator-activated receptor-gamma coactivator-1β (PGC-1β) is a transcriptional regulator whose increased expression activates energy expenditure-related genes in skeletal muscles. However, how PGC-1β is regulated remains largely unclear. Here, we show...
4.
Kamei Y, Hatazawa Y, Uchitomi R, Yoshimura R, Miura S
Nutrients
. 2020 Jan;
12(1).
PMID: 31963899
Amino acids are components of proteins that also exist free-form in the body; their functions can be divided into (1) nutritional, (2) sensory, and (3) biological regulatory roles. The skeletal...
5.
Nakai S, Uchitomi R, Matsuda R, Onishi T, Hatazawa Y, Kamei Y
Data Brief
. 2019 Aug;
23:103814.
PMID: 31372459
PGC-1β is a transcriptional co-activator of nuclear receptors, which acts to increase energy expenditure. PGC-1β fused to GAL4 DNA-binding domain transfected in HEK293T cells showed a reporter luciferase activity. We...
6.
Uchitomi R, Hatazawa Y, Senoo N, Yoshioka K, Fujita M, Shimizu T, et al.
Sci Rep
. 2019 Jul;
9(1):10425.
PMID: 31320689
Sarcopenia is the age-induced, progressive loss of skeletal muscle mass and function. To better understand changes in skeletal muscle during sarcopenia, we performed a metabolomic analysis of skeletal muscle in...
7.
Matsuda R, Uchitomi R, Oyabu M, Hatazawa Y, Kamei Y
FEBS Lett
. 2019 May;
593(12):1303-1312.
PMID: 31111473
The transcription factor FOXO1 is considered to play roles in the regulation of energy metabolism in various tissues. To determine the metabolic changes occurring due to FOXO1 activation, we analyzed...
8.
Uchitomi R, Nakai S, Matsuda R, Onishi T, Miura S, Hatazawa Y, et al.
Biochem Biophys Rep
. 2018 Dec;
17:51-55.
PMID: 30582007
PGC-1β is a transcriptional co-activator of nuclear receptors such as the estrogen receptor-related receptor (ERR). Transgenic overexpression of PGC-1β in mice increases energy expenditure and suppresses high-fat diet-induced obesity. In...
9.
Takigawa K, Matsuda R, Uchitomi R, Onishi T, Hatazawa Y, Kamei Y
Biosci Biotechnol Biochem
. 2018 Dec;
83(3):518-524.
PMID: 30537907
We examined the effect of long-term exercise on the prevention of sarcopenia using a senescence-accelerated-prone mice (SAMP8) model. Mice were housed in a wheel cage for 25 weeks to increase...
10.
Hirose Y, Onishi T, Miura S, Hatazawa Y, Kamei Y
J Nutr Sci Vitaminol (Tokyo)
. 2018 Jul;
64(3):229-232.
PMID: 29962435
Vitamin D is known to be effective for the prevention of muscle atrophy, such as age-related sarcopenia. However, vitamin D action in skeletal muscle tissue and muscle cells is largely...