Yukiko Nasu-Nishimura
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Explore the profile of Yukiko Nasu-Nishimura including associated specialties, affiliations and a list of published articles.
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15
Citations
413
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Recent Articles
1.
Funato K, Hayashi T, Echizen K, Negishi L, Shimizu N, Koyama-Nasu R, et al.
EMBO Rep
. 2018 Sep;
19(11).
PMID: 30213795
Glioblastoma is one of the most aggressive forms of cancers and has a poor prognosis. Genomewide analyses have revealed that a set of core signaling pathways, the p53, RB, and...
2.
Nakamura T, Sakaue F, Nasu-Nishimura Y, Takeda Y, Matsuura K, Akiyama T
EBioMedicine
. 2018 Jul;
34:189-200.
PMID: 30045817
GABAergic dysfunction underlies many neurodevelopmental and psychiatric disorders. GABAergic synapses exhibit several forms of plasticity at both pre- and postsynaptic levels. NMDA receptor (NMDAR)-dependent inhibitory long-term potentiation (iLTP) at GABAergic...
3.
Nakamura T, Arima-Yoshida F, Sakaue F, Nasu-Nishimura Y, Takeda Y, Matsuura K, et al.
Nat Commun
. 2016 Mar;
7:10861.
PMID: 26979507
Jacobsen syndrome (JBS) is a rare congenital disorder caused by a terminal deletion of the long arm of chromosome 11. A subset of patients exhibit social behavioural problems that meet...
4.
Hiraoka K, Hayashi T, Kaneko R, Nasu-Nishimura Y, Koyama-Nasu R, Kawasaki Y, et al.
Biochem Biophys Res Commun
. 2015 Mar;
460(2):216-21.
PMID: 25770425
LGR5 plays an important role in the self-renewal of stem cells and is used as a marker identifying self-renewing stem cells in small intestine and hair follicles. Moreover, LGR5 has...
5.
Koyama-Nasu R, Hayashi T, Nasu-Nishimura Y, Akiyama T, Yamanaka R
Biochem Biophys Res Commun
. 2015 Mar;
459(3):411-5.
PMID: 25735981
Upon binding of a Wnt ligand to the frizzled (FZD)-low density lipoprotein receptor related protein 5/6 (LRP5/6) receptor complex, the β-catenin destruction complex, composed of Axin1, adenomatous polyposis coli (APC),...
6.
Takai H, Masuda K, Sato T, Sakaguchi Y, Suzuki T, Suzuki T, et al.
Cell Rep
. 2014 Oct;
9(1):48-60.
PMID: 25284789
The development of cancer is driven not only by genetic mutations but also by epigenetic alterations. Here, we show that TET1-mediated production of 5-hydroxymethylcytosine (5hmC) is required for the tumorigenicity...
7.
Koyama-Nasu R, Takahashi R, Yanagida S, Nasu-Nishimura Y, Oyama M, Kozuka-Hata H, et al.
PLoS One
. 2013 Jan;
8(1):e53710.
PMID: 23326490
The pentaspan membrane glycoprotein CD133 (also known as prominin-1) has been widely used as a marker for both cancer and normal stem cells. However, the function of CD133 has not...
8.
Lussier M, Herring B, Nasu-Nishimura Y, Neutzner A, Karbowski M, Youle R, et al.
Proc Natl Acad Sci U S A
. 2012 Nov;
109(47):19426-31.
PMID: 23129617
AMPA receptors (AMPARs) mediate the majority of fast excitatory neurotransmission, and their density at postsynaptic sites determines synaptic strength. Ubiquitination is a posttranslational modification that dynamically regulates the synaptic expression...
9.
Kozuka-Hata H, Nasu-Nishimura Y, Koyama-Nasu R, Ao-Kondo H, Tsumoto K, Akiyama T, et al.
PLoS One
. 2012 Aug;
7(8):e43398.
PMID: 22912867
Background: Glioblastoma is one of the most aggressive tumors with poor prognosis. Although various studies have been performed so far, there are not effective treatments for patients with glioblastoma. Methodology/principal...
10.
Lussier M, Nasu-Nishimura Y, Roche K
J Neurosci
. 2011 Mar;
31(8):3077-81.
PMID: 21414928
AMPA receptors (AMPARs) are postsynaptic glutamate-gated ion channels that mediate fast excitatory neurotransmission in the mammalian brain. Synaptic activity modulates the density of synaptic AMPARs, thereby affecting synaptic function, learning,...