Yuki Toyama
Overview
Explore the profile of Yuki Toyama including associated specialties, affiliations and a list of published articles.
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51
Citations
282
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Recent Articles
1.
De D, Thapliyal N, Tiwari V, Toyama Y, Hansen D, Kay L, et al.
Proc Natl Acad Sci U S A
. 2024 Dec;
121(50):e2416682121.
PMID: 39630857
Despite the tremendous accomplishments of AlpaFold2/3 in predicting biomolecular structure, the protein folding problem remains unsolved in the sense that accurate atomistic models of how protein molecules fold into their...
2.
Toyama Y, Shimada I
J Biomol NMR
. 2024 Jun;
78(4):215-235.
PMID: 38918317
Solution NMR spectroscopy is a particularly powerful technique for characterizing the functional dynamics of biomolecules, which is typically achieved through the quantitative characterization of chemical exchange processes via the measurement...
3.
Toyama Y, Shimada I
Nat Commun
. 2024 Apr;
15(1):3303.
PMID: 38664397
The DEAD-box RNA helicase (DDX) plays a central role in many aspects of RNA metabolism by remodeling the defined structure of RNA molecules. While a number of structural studies have...
4.
Harkness R, Zhao H, Toyama Y, Schuck P, Kay L
J Am Chem Soc
. 2024 Mar;
146(12):8242-8259.
PMID: 38477967
The DegP protease-chaperone operates within the periplasm of Gram-negative bacteria, where it assists in the regulation of protein homeostasis, promotes virulence, and is essential to survival under stress. To carry...
5.
Rangadurai A, Toyama Y, Kay L
J Magn Reson
. 2023 Mar;
349:107412.
PMID: 36907132
The measurement of spin relaxation rates provides a unique avenue for quantifying dynamic processes in biomolecules. In order to simplify analysis of the measurements so that a few key intuitive...
6.
Toyama Y, Fujita Y, Toshima S, Hirano T, Yamasaki M, Kunitake H
Plants (Basel)
. 2023 Feb;
12(4).
PMID: 36840296
Polyphenol-rich rabbiteye blueberry ( Aiton) leaves have attracted attention as a food material. In this study, we compared the total polyphenols, total proanthocyanidin content, and antioxidant activity of the leaves...
7.
Rangadurai A, Toyama Y, Kay L
J Magn Reson
. 2023 Feb;
349:107400.
PMID: 36796143
Electrostatic interactions can play important roles in regulating various biological processes. Quantifying surface electrostatics of biomolecules is, therefore, of significant interest. Recent advances in solution NMR spectroscopy have enabled site-specific...
8.
Bolik-Coulon N, Sever A, Harkness R, Aramini J, Toyama Y, Hansen D, et al.
J Magn Reson
. 2022 Dec;
346:107326.
PMID: 36508761
The HMQC pulse sequence and variants thereof have been exploited in studies of high molecular weight protein complexes, taking advantage of the fact that fast and slow relaxing magnetization components...
9.
Toyama Y, Rangadurai A, Forman-Kay J, Kay L
J Biol Chem
. 2022 Dec;
299(1):102776.
PMID: 36496075
Biomolecular condensates concentrate proteins, nucleic acids, and small molecules and play an essential role in many biological processes. Their formation is tuned by a balance between energetically favorable and unfavorable...
10.
Toyama Y, Rangadurai A, Forman-Kay J, Kay L
Proc Natl Acad Sci U S A
. 2022 Aug;
119(36):e2210492119.
PMID: 36040869
Electrostatic interactions and charge balance are important for the formation of biomolecular condensates involving proteins and nucleic acids. However, a detailed, atomistic picture of the charge distribution around proteins during...