Yukang Lin
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Explore the profile of Yukang Lin including associated specialties, affiliations and a list of published articles.
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44
Citations
1339
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Recent Articles
1.
Zhang B, Li Y, Lin Y, Wang T, Chen L, Cai J, et al.
J Med Chem
. 2025 Jan;
68(2):1693-1715.
PMID: 39772543
CDK2 and CDK9 play pivotal roles in cell cycle progression and gene transcription, respectively, making them promising targets for cancer treatment. Herein, we discovered a series of -(substituted thiazol-2-yl)--(4-substituted phenyl)pyrimidine-2,4-diamines...
2.
Xiang L, Qin Y, Li L, Xiang X, Zhang W, Jiao Q, et al.
Int J Pharm
. 2024 Dec;
669():125058.
PMID: 39653289
Liver fibrosis is a pathological condition marked by the excessive buildup of extracellular matrix primarily resulting from the transformation of quiescent hepatic stellate cells (HSCs) to myofibroblastic (MF) phenotype and...
3.
Chen W, Liao L, Huang Z, Lu Y, Lin Y, Pei Y, et al.
Front Pharmacol
. 2024 Apr;
15:1394753.
PMID: 38560352
[This corrects the article DOI: 10.3389/fphar.2022.943119.].
4.
Jiang S, Chen Q, Xiang Y, Pan Y, Wu X, Lin Y
Neural Netw
. 2024 Feb;
173:106173.
PMID: 38387200
The excellent generalization, contextual learning, and emergence abilities in the pre-trained large models (PLMs) handle specific tasks without direct training data, making them the better foundation models in the adversarial...
5.
Yang X, Tian M, Lin Y, Li L, Sun X, Zhang Z, et al.
Hum Gene Ther
. 2023 Mar;
34(11-12):495-517.
PMID: 36932739
This study was aimed to analyze the diagnostic, therapeutic, and prognostic value of the suppressor of cytokine signaling 3 (SOCS3) in pancancer, especially in esophageal carcinoma (ESCA), and investigate the...
6.
Chen W, Liao L, Huang Z, Lu Y, Lin Y, Pei Y, et al.
Front Pharmacol
. 2022 Dec;
13:943119.
PMID: 36452228
Irritable bowel syndrome (IBS) is usually associated with chronic gastrointestinal disorders. Its most common subtype is accompanied with diarrhea (IBS-D). The enteric nervous system (ENS) modulates major gastrointestinal motility and...
7.
Yang X, Shen Z, Tian M, Lin Y, Li L, Chai T, et al.
Transl Oncol
. 2022 Aug;
24:101487.
PMID: 35917643
Increasing evidence has indicated that long non-coding RNAs (LncRNAs) play multiple functions in the development of cancer and function as indicators of diagnosis and prognosis. This aim of this study...
8.
Yang L, Hong Z, Lin Z, Chen M, Yang X, Lin Y, et al.
Esophagus
. 2022 Jul;
20(1):89-98.
PMID: 35900684
Background: Anastomotic mediastinal/pleural cavity leak (AMPCL) is a life-threatening postoperative complication after esophagectomy. The objective of this study was to find a safe and effective surgical method to reduce the...
9.
Zhang Z, Xie S, Cai W, Hong Z, Yang C, Lin Y, et al.
Transl Lung Cancer Res
. 2022 Mar;
11(1):75-86.
PMID: 35242629
Background: Large part of patients of stage IB non-small cell lung cancer (IB NSCLC) may suffer recurrence after surgery. This study is to determine risk factors and establish a nomogram...
10.
Zhang Z, Hong Z, Xie S, Lin W, Lin Y, Zhu J, et al.
Ann Transl Med
. 2021 Dec;
9(21):1623.
PMID: 34926667
Background: To investigate the safety and feasibility of combining neoadjuvant sintilimab (Innovent Biologics, Suzhou, China) and chemotherapy for locally advanced esophageal squamous cell carcinoma (ESCC). Methods: The study was an...