Yujun Shen
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Explore the profile of Yujun Shen including associated specialties, affiliations and a list of published articles.
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104
Citations
1341
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Recent Articles
1.
Mei Q, Zhang Y, Li H, Ma W, Huang W, Wu Z, et al.
Cell Death Differ
. 2025 Feb;
PMID: 39972058
Intrahepatic cholangiocarcinoma (ICC) is characterized by poor prognosis and limited treatment. Hepatocytes have been considered as one of the origins of ICC, however, the underlying mechanisms remain unclear. Here, we...
2.
Yang X, Xiao X, Zhou L, Shen Y, Wang L, Shen Q
Exp Lung Res
. 2025 Jan;
51(1):1-10.
PMID: 39861940
Acute lung injury (ALI) is a severe respiratory disease with high mortality, mainly due to overactivated oxidative stress and subsequent pyroptosis. Mesencephalic astrocyte-derived neurotrophic factor (MANF), an inducible secretory endoplasmic...
3.
Zhao M, Zhou L, Zhang Q, Wang M, Dong Y, Wang Y, et al.
Adv Sci (Weinh)
. 2025 Jan;
12(10):e2407900.
PMID: 39840525
Colorectal cancer (CRC) usually creates an immunosuppressive microenvironment, thereby hindering immunotherapy response. Effective treatment options remain elusive. Using scRNA-seq analysis in a tumor-bearing murine model, it is found that lobeline,...
4.
Xu Y, Liao P, Song X, Guo W, Liu B, Ye T, et al.
Respir Res
. 2025 Jan;
26(1):26.
PMID: 39827111
This study introduced a novel dual fixation method for the pulmonary vasculature and lung tissue in pulmonary hypertension (PH) rats, addressing the limitations of traditional fixation methods that failed to...
5.
Wang C, Yu T, Wang Y, Xu M, Wang J, Zhao Y, et al.
Mucosal Immunol
. 2025 Jan;
PMID: 39746548
Inflammatory bowel diseases (IBDs) are characterized by unrestrained innate and adaptive immune responses and compromised intestinal epithelial barrier integrity. Regulatory T (T) cells are crucial for maintaining self-tolerance and immune...
6.
Ren H, Mu C, Wang Y, Cheng Y, Hou Y, Li Y, et al.
J Am Soc Nephrol
. 2025 Jan;
PMID: 39745791
No abstract available.
7.
Shao J, Wang W, Li S, Yin G, Han L, Wang X, et al.
Adv Sci (Weinh)
. 2024 Dec;
12(6):e2411988.
PMID: 39679869
Emerging evidence suggests that the sterile alpha-motif (SAM) and histidine-aspartate (HD) domain-containing protein 1 (SAMHD1) is implicated in various cancers, including hepatocellular carcinoma (HCC). However, its precise role in tumor...
8.
Wang X, Wang L, Zhou Z, Jiang C, Bao Z, Wang Y, et al.
Cell Rep
. 2024 Dec;
43(12):115033.
PMID: 39643968
The Ada two A-containing (ATAC) complex, containing histone acetyltransferases general control non-derepressible 5 (GCN5) or p300/CBP-associated factor (PCAF), has gained recognition as a prominent transcriptional coactivator. Recent revelations unveiled E3...
9.
Shen Y, Wang J, Liang J, Chen Y, Wu X, Ren Z, et al.
CNS Neurosci Ther
. 2024 Nov;
30(11):e70136.
PMID: 39614674
Aim: Cerebral ischemic stroke (IS) is one of the leading causes of morbidity and mortality globally. However, the mechanisms underlying IS injury remain poorly understood. Ring finger protein 2 (RNF2),...
10.
Han D, Ma Q, Ballar P, Zhang C, Dai M, Luo X, et al.
Acta Pharm Sin B
. 2024 Nov;
14(10):4396-4412.
PMID: 39525584
In advanced hepatocellular carcinoma (HCC) tissues, M2-like tumor-associated macrophages (TAMs) are in the majority and promotes HCC progression. Contrary to the pro-tumor effect of M2-like TAMs, M1-like TAMs account for...