Yuh-Charn Lin
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Explore the profile of Yuh-Charn Lin including associated specialties, affiliations and a list of published articles.
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25
Citations
543
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Recent Articles
1.
Lee K, Lin Y, Tsai M, Tu C, Ou S, Chen H, et al.
J Microbiol Immunol Infect
. 2024 Jul;
57(5):720-729.
PMID: 39034165
Background: The adverse effects of sepsis-associated acute kidney injury (SA-AKI) highlight the need for new biomarkers. Signal Peptide-Complement C1r/C1s, Uegf, Bmp1-Epidermal Growth Factor-like Domain-Containing Protein 2 (SCUBE2), important for angiogenesis...
2.
Lin Y, Chang Y, Gau S, Lo C, Yang R
Cardiovasc Res
. 2024 Jun;
120(13):1636-1649.
PMID: 38870316
Aims: SCUBE2 (signal peptide-CUB-epidermal growth factor-like domain-containing protein 2) is a secreted or membrane-bound protein originally identified from endothelial cells (ECs). Our previous work showed that SCUBE2 forms a complex...
3.
Lin Y, Sahoo B, Gau S, Yang R
J Biomed Sci
. 2023 May;
30(1):33.
PMID: 37237303
The SCUBE [Signal peptide-Complement C1r/C1s, Uegf, Bmp1 (CUB)-Epithelial growth factor domain-containing protein] family consists of three proteins in vertebrates, SCUBE1, 2 and 3, which are highly conserved in zebrafish, mice...
4.
Sahoo B, Lin Y, Tu C, Lin C, Liao W, Li F, et al.
Haematologica
. 2022 Aug;
108(5):1284-1299.
PMID: 36005562
A hallmark of mixed lineage leukemia gene-rearranged (MLL-r) acute myeloid leukemia that offers an opportunity for targeted therapy is addiction to protein tyrosine kinase signaling. One such signal is the...
5.
Liu Y, Guerrero-Juarez C, Xiao F, Shettigar N, Ramos R, Kuan C, et al.
Dev Cell
. 2022 Jul;
57(14):1758-1775.e7.
PMID: 35777353
Hair follicle stem cells are regulated by dermal papilla fibroblasts, their principal signaling niche. Overactivation of Hedgehog signaling in the niche dramatically accelerates hair growth and induces follicle multiplication in...
6.
Chou P, Liu C, Weng C, Yang K, Cheng M, Lin Y, et al.
Circ Res
. 2022 May;
131(1):6-20.
PMID: 35611699
Background: The sino atrial node (SAN) is characterized by the microenvironment of pacemaker cardiomyocytes (PCs) encased with fibroblasts. An altered microenvironment leads to rhythm failure. Operable cell or tissue models...
7.
Hu Y, Lee A, Chang S, Lin S, Weng C, Lo H, et al.
Nat Biomed Eng
. 2021 Nov;
6(4):421-434.
PMID: 34811487
Pacemaker cells can be differentiated from stem cells or transdifferentiated from quiescent mature cardiac cells via genetic manipulation. Here we show that the exposure of rat quiescent ventricular cardiomyocytes to...
8.
Zebrafish Scube1 and Scube2 cooperate in promoting Vegfa signalling during embryonic vascularization
Tsao K, Lin Y, Chen Y, Lai S, Yang R
Cardiovasc Res
. 2021 Mar;
118(4):1074-1087.
PMID: 33788916
Aims: The secreted and membrane-anchored signal peptide-CUB-EGF domain-containing proteins (SCUBE) gene family composed of three members was originally identified from endothelial cells (ECs). We recently showed that membrane SCUBE2 binds...
9.
Lin Y, Niceta M, Muto V, Vona B, Pagnamenta A, Maroofian R, et al.
Am J Hum Genet
. 2020 Dec;
108(1):115-133.
PMID: 33308444
Signal peptide-CUB-EGF domain-containing protein 3 (SCUBE3) is a member of a small family of multifunctional cell surface-anchored glycoproteins functioning as co-receptors for a variety of growth factors. Here we report...
10.
Chen J, Kuo K, Bamodu O, Lin Y, Yang R, Yeh C, et al.
Exp Cell Res
. 2018 Jul;
370(2):444-453.
PMID: 29981340
Background: Metastatic and/or recurrent breast carcinomas are leading causes of cancer-related death worldwide. Breast cancer stem cells (BCSCs) have been implicated in cancer metastases and progression, thus, the need for...