Alpha 2.0
Login Register
» Authors » Yuet W Kan

Yuet W Kan

Explore the profile of Yuet W Kan including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 7
Citations 77
Followers 0
Related Specialties
Hematology
Biology
Pharmacology
Top 10 Co-Authors
Hua Su
R Geoffrey Sargent
Dieter C Gruenert
Paolo Moi
Shingo Suzuki
Isadora Asunis
Hirofumi Kai
M Giuseppina Marini
Tsuyoshi Shuto
Lin Ye
Published In
Blood Cells Mol Dis
Radiology
Front Genome Ed
Mol Ther
Mol Ther Nucleic Acids
Affiliations
Soon will be listed here.
Recent Articles
1.
Seamless Gene Correction in the Human Cystic Fibrosis Transmembrane Conductance Regulator Locus by Vector Replacement and Vector Insertion Events
Suzuki S, Chosa K, Barilla C, Yao M, Zuffardi O, Kai H, et al.
Front Genome Ed . 2022 Apr; 4:843885. PMID: 35465025
Gene correction homology directed repair (HDR) in patient-derived induced pluripotent stem (iPS) cells for regenerative medicine are becoming a more realistic approach to develop personalized and mutation-specific therapeutic strategies due...
2.
Induction of therapeutic levels of HbF in genome-edited primary β 39-thalassaemia haematopoietic stem and progenitor cells
Mingoia M, Caria C, Ye L, Asunis I, Marongiu M, Manunza L, et al.
Br J Haematol . 2020 Nov; 192(2):395-404. PMID: 33216968
Hereditary persistence of fetal haemoglobin (HPFH) is the major modifier of the clinical severity of β-thalassaemia. The homozygous mutation c.-196 C>T in the Aγ-globin (HBG1) promoter, which causes Sardinian δβ...
3.
TALENs Facilitate Single-step Seamless SDF Correction of F508del CFTR in Airway Epithelial Submucosal Gland Cell-derived CF-iPSCs
Suzuki S, Sargent R, Illek B, Fischer H, Esmaeili-Shandiz A, Yezzi M, et al.
Mol Ther Nucleic Acids . 2016 Jan; 5:e273. PMID: 26730810
Cystic fibrosis (CF) is a recessive inherited disease associated with multiorgan damage that compromises epithelial and inflammatory cell function. Induced pluripotent stem cells (iPSCs) have significantly advanced the potential of...
4.
Permanent coronary artery occlusion: cardiovascular MR imaging is platform for percutaneous transendocardial delivery and assessment of gene therapy in canine model
Saeed M, Martin A, Jacquier A, Bucknor M, Saloner D, Do L, et al.
Radiology . 2008 Sep; 249(2):560-71. PMID: 18780824
Purpose: To provide evidence that vascular endothelial growth factor (VEGF) genes delivered transendocardially with magnetic resonance (MR) imaging guidance may neovascularize or improve vascular recruitment in occlusive infarction. Materials And...
5.
Recombinant adeno-associated viral vector encoding human VEGF165 induces neomicrovessel formation in the adult mouse brain
Shen F, Su H, Liu W, Kan Y, Young W, Yang G
Front Biosci . 2006 May; 11:3190-8. PMID: 16720385
Delivery of therapeutic genes represents a fascinating possibility to accelerate injury-repairing process in tissues that are otherwise difficult to treat, such as cerebral ischemia. Current studies indicate that gene transfer-induced...
6.
Adeno-associated viral vector-mediated gene transfer of VEGF normalizes skeletal muscle oxygen tension and induces arteriogenesis in ischemic rat hindlimb
Chang D, Su H, Tang G, Brevetti L, Sarkar R, Wang R, et al.
Mol Ther . 2003 Feb; 7(1):44-51. PMID: 12573617
Critical limb ischemia is an important clinical problem that often leads to disability and limb loss. Vascular endothelial growth factor (VEGF), delivered either as recombinant protein or as gene therapy,...
7.
Cloning MafF by recognition site screening with the NFE2 tandem repeat of HS2: analysis of its role in globin and GCSl genes regulation
Marini M, Asunis I, Chan K, Chan J, Kan Y, Porcu L, et al.
Blood Cells Mol Dis . 2002 Dec; 29(2):145-58. PMID: 12490281
The erythroid-specific enhancer within hypersensitivity site 2 (HS2) of the human beta-globin locus control region is required for high level globin gene expression. We used an oligonucleotide of the NF-E2...